Detalhe da pesquisa
1.
Unveiling Gambogenic Acid as a Promising Antitumor Compound: A Review.
Planta Med
; 90(5): 353-367, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38295847
2.
Identification of in vivo metabolites of a potential anti-rheumatoid arthritis compound, the quinazolinone derivative PD110, using ultra-high performance liquid chromatography coupled with Q-Exactive plus mass spectrometrys.
Xenobiotica
; 52(3): 284-294, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377274
3.
p53-dependent apoptosis is essential for the antitumor effect of paclitaxel response to DNA damage in papillary thyroid carcinoma.
Int J Med Sci
; 18(14): 3197-3205, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400889
4.
Modulation of LPS-induced inflammation in RAW264.7 murine cells by novel isoflavonoids from Millettia pulchra.
Bioorg Chem
; 97: 103693, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32120079
5.
The effect and mechanism of millepachine-disrupted spindle assembly in tumor cells.
Anticancer Drugs
; 29(5): 449-456, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29649038
6.
Millepachine showed novel antitumor effects in cisplatin-resistant human ovarian cancer through inhibiting drug efflux function of ATP-binding cassette transporters.
Phytother Res
; 32(12): 2428-2435, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30123958
7.
Barbigerone reverses multidrug resistance in breast MCF-7/ADR cells.
Phytother Res
; 32(4): 733-740, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29368443
8.
Discovery of a potent microtubule-targeting agent: Synthesis and biological evaluation of water-soluble amino acid prodrug of combretastatin A-4 derivatives.
Bioorg Med Chem Lett
; 25(11): 2302-7, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25933592
9.
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
Bioorg Med Chem
; 23(13): 3337-50, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937236
10.
Separation of flavonoids from Millettia griffithii with high-performance counter-current chromatography guided by anti-inflammatory activity.
J Sep Sci
; 38(3): 523-9, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25413585
11.
SKLB-M8 induces apoptosis through the AKT/mTOR signaling pathway in melanoma models and inhibits angiogenesis with decrease of ERK1/2 phosphorylation.
J Pharmacol Sci
; 126(3): 198-207, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25341684
12.
Genes in Axonal Regeneration.
Mol Neurobiol
; 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388774
13.
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Phytomedicine
; 129: 155670, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704915
14.
Causal effect of gut microbiota of Defluviitaleaceae on the clinical pathway of "Influenza-Subacute Thyroiditis-Hypothyroidism".
Front Microbiol
; 15: 1354989, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38476943
15.
NU6300 covalently reacts with cysteine-191 of gasdermin D to block its cleavage and palmitoylation.
Sci Adv
; 10(6): eadi9284, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38324683
16.
Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
J Med Chem
; 67(9): 7516-7538, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38686671
17.
Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Carcinogenesis
; 34(7): 1636-43, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23471882
18.
Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
Bioorg Med Chem
; 21(21): 6844-54, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23993668
19.
Regulation of Schwann cell proliferation and migration via miR-195-5p-induced Crebl2 downregulation upon peripheral nerve damage.
Front Cell Neurosci
; 17: 1173086, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37469605
20.
Diagnostic performance of ultrasound risk stratification systems on thyroid nodules cytologically classified as indeterminate: a systematic review and meta-analysis.
Ultrasonography
; 42(4): 518-531, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697824