RESUMO
A direct method has been developed for iodine-mediated thiolation of naphthols/naphthylamines and arylsulfonyl hydrazides through the formation of C-S bond and cleavage of S-N/S-O bonds. In this transformation, a range of valuable thioethers are easily achieved in moderate to good yields.
Assuntos
1-Naftilamina/química , Iodo/química , Naftóis/química , Compostos de Sulfidrila/química , Sulfetos/síntese química , Catálise , Ligação de Hidrogênio , Estrutura Molecular , Sulfetos/químicaRESUMO
A direct method for the synthesis of 1,3,4-triarylpyrroles was achieved easily from cyclization of α-amino carbonyl compounds and aldehydes catalyzed by I2. Various substituted groups can be employed, and this reaction can proceed smoothly in moderate to good yields.
Assuntos
Aldeídos/química , Pirróis/síntese química , Catálise , Estrutura Molecular , Pirróis/químicaRESUMO
A direct method for the synthesis of substituted indolizines by means of I2-mediated oxidative tandem cyclization via C-N/C-C bond formation was developed. Various substituted aromatic/aliphatic enolizable aldehydes and 2-pyridylacetates/acetonitrile/acetone proceeded smoothly in this transformation, and the desired products were generated in moderate to good yields.
Assuntos
Acetonitrilas/química , Indolizinas/síntese química , Iodo/química , Piridinas/química , Catálise , Ciclização , Indolizinas/química , Estrutura Molecular , OxirreduçãoRESUMO
A novel and efficient I2-catalyzed oxidative tandem cyclization of simple vinyl azides and benzylamines has been developed for the synthesis of substituted imidazoles. In this reaction, various substituted groups on vinyl azides and benzylamines proceed smoothly and the desired imidazoles are obtained in moderate to good yields.
Assuntos
Azidas/química , Benzilaminas/química , Imidazóis/química , Imidazóis/síntese química , Iodo/química , Catálise , Técnicas de Química SintéticaRESUMO
A novel iodine-mediated oxidative tandem cyclization reaction of simple enaminones has been developed for the synthesis of substituted furopyridines through C-C/C-N/C-O bond formation in a one-pot procedure. Substituted furopyridines are obtained in moderate to good yield. In addition, I- and Br-substituted furopyridines have been successfully produced by the electrophilic substitution of N-iodo- or N-bromosuccinimide.