1.
Org Biomol Chem
; 17(15): 3723-3726, 2019 04 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30907392
RESUMO
A mild and efficient method for the synthesis of cyanoformamides from N,N-disubstituted aminomalononitriles with CsF as the promoter has been developed. This method features a wide substrate scope and high reaction efficiency, and will facilitate corresponding cyanoformamide-based biological studies and synthetic methodology development.
2.
Chem Commun (Camb)
; 56(55): 7641-7644, 2020 Jul 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32519681
RESUMO
An efficient alkylcyanation of in situ generated arynes by N,N-disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.