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1.
Front Plant Sci ; 15: 1358360, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38486848

RESUMO

Introduction: In contemporary agronomic research, the focus has increasingly shifted towards non-destructive imaging and precise phenotypic characterization. A photon-counting micro-CT system has been developed, which is capable of imaging lychee fruit at the micrometer level and capturing a full energy spectrum, thanks to its advanced photon-counting detectors. Methods: For automatic measurement of phenotypic traits, seven CNN-based deep learning models including AttentionUNet, DeeplabV3+, SegNet, TransUNet, UNet, UNet++, and UNet3+ were developed. Machine learning techniques tailored for small-sample training were employed to identify key characteristics of various lychee species. Results: These models demonstrate outstanding performance with Dice, Recall, and Precision indices predominantly ranging between 0.90 and 0.99. The Mean Intersection over Union (MIoU) consistently falls between 0.88 and 0.98. This approach served both as a feature selection process and a means of classification, significantly enhancing the study's ability to discern and categorize distinct lychee varieties. Discussion: This research not only contributes to the advancement of non-destructive plant analysis but also opens new avenues for exploring the intricate phenotypic variations within plant species.

2.
Phys Med Biol ; 69(12)2024 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-38776955

RESUMO

Objective.To assess potential variations in the absorbed dose between Chinese and Caucasian children exposed to18F-FDG PET scan and to investigate the factors contributing to dose differences, this work employed patient-specific phantoms and our compartment model for calculating the patient-specific absorbed dose in Chinese children.Approach.Data of 29 Chinese pediatric patients undergoing whole-body18F-FDG PET/CT studies were retrospectively collected, including PET images for activity distributions and corresponding CT images for organ segmentation and phantom construction. A biokinetic compartment model was implemented to obtain cumulated activities. Absorbed radiation dose for both CT and PET component were calculated using Monte Carlo simulations. Regression models were fitted to time integrated activity coefficient (TIAC) and organ absorbed dose for each patient.Main results.TIACs of all the organs in our compartment model and the organ dose for 12 organs were correlated with patients' weight. Young children have significantly large uptake in brain compared to adults. The distinctions of anatomical and biological characteristics between Chinese and Caucasian children contribute to variations in the absorbed dose of18F-FDG PET scans. PET contributed more in organ dose than CT did in most organs, especially in brain and bladder. The average effective dose (± SD) was 4.5 mSv (± 1.12 mSv), 7.8 mSv (± 3.2 mSv) and 12.3 mSv (± 3.5 mSv) from CT, PET and their sum respectively. PET contributed 1.7 times higher than CT.Significance.To the best of our knowledge, this work represents the first attempt to estimate patient-specific radiation doses from PET/CT for Chinese pediatric patients. TIACs derived from our methodology in both age groups exhibited significant differences from the that reported in ICRP 128. Substantial differences in absorbed and effective doses were observed between Chinese and Caucasian children across all age groups. These disparities are attributed to markedly distinct anatomical and pharmacokinetic characteristics among adults and pediatric patients, and different racial groups. The application of data derived from adults to pediatric patients introduces considerable uncertainty. Our methodology offers a valuable approach not only for estimating pharmacokinetic characteristics and patient-specific radiation doses in pediatric patients undergoing18F-FDG studies but also for other cohorts with similar characteristics.


Assuntos
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Doses de Radiação , Humanos , Criança , Masculino , Pré-Escolar , Feminino , Povo Asiático , Imagem Corporal Total/métodos , Adolescente , Lactente , Imagens de Fantasmas , Fluordesoxiglucose F18 , Método de Monte Carlo , População do Leste Asiático
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