RESUMO
Labdane-type diterpenes, called excoecarins S, T1, and T2 were isolated from the resinous wood of Excoecaria agallocha, along with three known compounds, ent-12-oxo-2,3-secobeyer-15-ene-2,3-dioic acid, agallochin H, and ent-15-epoxy-beyerane-3alpha-ol. Their structures were elucidated on the basis of spectroscopic data, chemical evidence, and X-ray analysis.
Assuntos
Diterpenos/química , Diterpenos/isolamento & purificação , Euphorbiaceae/química , Cristalografia por Raios X , Estrutura Molecular , Ressonância Magnética Nuclear Biomolecular , MadeiraRESUMO
Two new bis-secolabdane diterpenoids, excoecarins R1 (1) and R2 (2), were isolated from the resinous wood of Excoecaria agallocha. The structures of 1 and 2 were established on the basis of spectroscopic data interpretation and chemical evidence.
Assuntos
Diterpenos/isolamento & purificação , Euphorbiaceae/química , Plantas Medicinais/química , Diterpenos/química , Hidrólise , Japão , Estrutura Molecular , Oxirredução , Casca de Planta/química , Estereoisomerismo , MadeiraRESUMO
Three new diterpenoids, excoecarins V1-V3 (1-3) and a new flavanone glycoside (7) were isolated from the fresh stem of Excoecaria agallocha L. Their structures were elucidated as: 2alpha,3alpha,18-trihydroxy-3beta,20-epoxybeyer-15-ene (1), ent-2,3-secokaur-16-en-2,3-dioic acid (2), ent-3,4-seco-16alpha-hydroxyatis-4(19)-en-3-oic acid (3), and 3,5,7,3',5'-pentahydroxy-2R,3R-flavanonol 3-O-alpha-L-rhamnopyranoside (7) on the basis of spectroscopic data, chemical evidence, and/or X-ray analysis.