Detalhe da pesquisa
1.
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries.
J Am Chem Soc
; 145(46): 25283-25292, 2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857329
2.
L-OPA1 deficiency aggravates necroptosis of alveolar epithelial cells through impairing mitochondrial function during acute lung injury in mice.
J Cell Physiol
; 237(7): 3030-3043, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35478455
3.
Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer.
Acta Pharmacol Sin
; 42(1): 149-159, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32451413
4.
Theoretical insights into the mechanism of ferroptosis suppression via inactivation of a lipid peroxide radical by liproxstatin-1.
Phys Chem Chem Phys
; 19(20): 13153-13159, 2017 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489094
5.
Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis.
Nat Struct Mol Biol
; 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388831
6.
Adamantaniline Derivatives Target ATP5B to Inhibit Translation of Hypoxia Inducible Factor-1α.
Adv Sci (Weinh)
; 10(25): e2301071, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37401167
7.
TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury.
Int J Biol Sci
; 19(1): 242-257, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36594089
8.
Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage.
Front Pharmacol
; 13: 902016, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36324684
9.
Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-ß1-Smad2/3 Signaling in a PPARγ-Dependent Manner.
Oxid Med Cell Longev
; 2022: 7265486, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36275905
10.
TREM-1 exacerbates bleomycin-induced pulmonary fibrosis by aggravating alveolar epithelial cell senescence in mice.
Int Immunopharmacol
; 113(Pt A): 109339, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36330909
11.
Mitochondrial citrate accumulation drives alveolar epithelial cell necroptosis in lipopolysaccharide-induced acute lung injury.
Exp Mol Med
; 54(11): 2077-2091, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36443565
12.
Extracellular citrate serves as a DAMP to activate macrophages and promote LPS-induced lung injury in mice.
Int Immunopharmacol
; 101(Pt B): 108372, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34810128
13.
Activation of NLRP3 inflammasome up-regulates TREM-1 expression in murine macrophages via HMGB1 and IL-18.
Int Immunopharmacol
; 89(Pt A): 107045, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045564
14.
Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule.
ACS Chem Biol
; 15(3): 632-639, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32069008
15.
Hydrolyzation of mogrosides: Immobilized ß-glucosidase for mogrosides deglycosylation from Lo Han Kuo.
Food Sci Nutr
; 7(2): 834-843, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30847162
16.
Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice.
J Med Chem
; 61(18): 8241-8254, 2018 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30074791