Detalhe da pesquisa
1.
YAP-dependent proliferation by a small molecule targeting annexin A2.
Nat Chem Biol
; 17(7): 767-775, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33723431
2.
New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice.
Bioconjug Chem
; 31(4): 1167-1176, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243137
3.
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.
Nat Chem Biol
; 13(8): 845-849, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28604693
4.
Recombinant thiopeptides containing noncanonical amino acids.
Proc Natl Acad Sci U S A
; 113(13): 3615-20, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26976568
5.
Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery.
Proc Natl Acad Sci U S A
; 113(15): 4140-5, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27035989
6.
Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
Chemistry
; 18(21): 6528-41, 2012 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22488888
7.
Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.
Chemistry
; 18(27): 8403-13, 2012 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22674877
8.
A peptide aldehyde microarray for high-throughput profiling of cellular events.
J Am Chem Soc
; 133(6): 1946-54, 2011 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21247160
9.
Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs).
J Am Chem Soc
; 133(31): 12009-20, 2011 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21732629
10.
Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities.
J Am Chem Soc
; 132(2): 656-66, 2010 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20028024
11.
High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.
Org Biomol Chem
; 7(9): 1821-8, 2009 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19590777
12.
Photoactivatable Fluorogenic Labeling via Turn-On "Click-Like" Nitroso-Diene Bioorthogonal Reaction.
Adv Sci (Weinh)
; 6(13): 1802039, 2019 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31380178
13.
Solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases.
Org Lett
; 10(10): 1881-4, 2008 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18407644
14.
A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli.
Angew Chem Int Ed Engl
; 52(19): 5106-9, 2013 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23554007
15.
Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models.
J Med Chem
; 61(7): 3218-3223, 2018 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29528634
16.
Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis.
Angew Chem Int Ed Engl
; 50(30): 6776-81, 2011 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21678537
17.
Design of Potent and Proteolytically Stable Oxyntomodulin Analogs.
ACS Chem Biol
; 11(2): 324-8, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26727558
18.
Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase.
ACS Chem Biol
; 9(5): 1092-6, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24506189
19.
Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei.
Chem Commun (Camb)
; 48(6): 835-7, 2012 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22124229
20.
Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes.
Chem Asian J
; 6(10): 2762-75, 2011 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21744505