Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.

Italiano, Antoine; Miller, Wilson H; Blay, Jean-Yves; Gietema, Jourik A; Bang, Yung-Jue; Mileshkin, Linda R; Hirte, Hal W; Higgins, Brian; Blotner, Steven; Nichols, Gwen L; Chen, Lin Chi; Petry, Claire; Yang, Qi Joy; Schmitt, Christophe; Jamois, Candice; Siu, Lillian L.

Invest New Drugs ; 39(6): 1587-1597, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34180037

2.

Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures.

Taam, Jason; Yang, Qi Joy; Pang, K Sandy; Karanicolas, Paul; Choi, Stephen; Wasowicz, Marcin; Jerath, Angela.

J Cardiothorac Vasc Anesth ; 34(3): 782-790, 2020 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-31455576

3.

Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D₃ kinetics for extrapolation from mouse to man: Commentary.

Noh, Keumhan; Yang, Qi Joy; Sekhon, Lavtej; Quach, Holly P; Chow, Edwin C Y; Pang, K Sandy.

Biopharm Drug Dispos ; 41(3): 126-148, 2020 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-32319119

4.

Highlighting Vitamin D Receptor-Targeted Activities of 1α,25-Dihydroxyvitamin D₃ in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling.

Yang, Qi Joy; Bukuroshi, Paola; Quach, Holly P; Chow, Edwin C Y; Pang, K Sandy.

Drug Metab Dispos ; 46(1): 75-87, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29084783

5.

Tranexamic Acid Dosing for Cardiac Surgical Patients With Chronic Renal Dysfunction: A New Dosing Regimen.

Jerath, Angela; Yang, Qi Joy; Pang, K Sandy; Looby, Nikita; Reyes-Garces, Nathaly; Vasiljevic, Tijana; Bojko, Barbara; Pawliszyn, Janusz; Wijeysundera, Duminda; Beattie, W Scott; Yau, Terrence M; Wasowicz, Marcin.

Anesth Analg ; 127(6): 1323-1332, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-29309319

6.

Unequivocal evidence supporting the segregated flow intestinal model that discriminates intestine versus liver first-pass removal with PBPK modeling.

Pang, K Sandy; Yang, Qi Joy; Noh, Keumhan.

Biopharm Drug Dispos ; 38(3): 231-250, 2017 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-27977852

7.

Comparing early liver graft function from heart beating and living-donors: A pilot study aiming to identify new biomarkers of liver injury.

Yang, Qi Joy; Kluger, Michael; Gorynski, Krzysztof; Pawliszyn, Janusz; Bojko, Barbara; Yu, Ai-Ming; Noh, Keumhan; Selzner, Markus; Jerath, Angela; McCluskey, Stuart; Pang, K Sandy; Wasowicz, Marcin.

Biopharm Drug Dispos ; 38(5): 326-339, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28102538

8.

Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.

Yang, Qi Joy; Fan, Jianghong; Chen, Shu; Liu, Lutan; Sun, Huadong; Pang, K Sandy.

Drug Metab Dispos ; 44(7): 1123-38, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27098743

9.

Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice.

Ramakrishnan, Vidya; Yang, Qi Joy; Quach, Holly P; Cao, Y; Chow, Edwin C Y; Mager, Donald E; Pang, K Sandy.

Drug Metab Dispos ; 44(2): 189-208, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26586377

10.

PBPK modeling to unravel nonlinear pharmacokinetics of verapamil to estimate the fractional clearance for verapamil N-demethylation in the recirculating rat liver preparation.

Yang, Qi Joy; Si, Luqin; Tang, Hui; Sveigaard, Helle H; Chow, Edwin C Y; Pang, K Sandy.

Drug Metab Dispos ; 43(4): 631-45, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25650380

11.

Pharmacokinetic modeling of tranexamic acid for patients undergoing cardiac surgery with normal renal function and model simulations for patients with renal impairment.

Yang, Qi Joy; Jerath, Angela; Bies, Robert R; Wasowicz, Marcin; Pang, K Sandy.

Biopharm Drug Dispos ; 36(5): 294-307, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25704361

12.

To the Editor.

Jerath, Angela; Yang, Qi Joy; Wasowicz, Marcin; Pang, K Sandy.

Anesth Analg ; 128(6): e125-e126, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-31094820

13.

Response to letter to the editor on "fractional clearance for verapamil N-demethylation in the isolated rat liver preparation".

Pang, K Sandy; Yang, Qi Joy.

Drug Metab Dispos ; 43(7): 1058-9, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25964425

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