Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Adherens junctions as molecular regulators of emergent tissue mechanics.

Campàs, Otger; Noordstra, Ivar; Yap, Alpha S.

Nat Rev Mol Cell Biol ; 25(4): 252-269, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38093099

2.

c-Src induced vascular malformations require localised matrix degradation at focal adhesions.

Essebier, Patricia; Keyser, Mikaela; Yordanov, Teodor; Hill, Brittany; Yu, Alexander; Noordstra, Ivar; Yap, Alpha S; Stehbens, Samantha J; Lagendijk, Anne K; Schimmel, Lilian; Gordon, Emma J.

J Cell Sci ; 2024 Jun 17.

Artigo em Inglês | MEDLINE | ID: mdl-38881365

3.

Dynamically regulated focal adhesions coordinate endothelial cell remodelling in developing vasculature.

Chau, Tevin C Y; Keyser, Mikaela S; Da Silva, Jason A; Morris, Elysse K; Yordanov, Teodor E; Duscyz, Kinga P; Paterson, Scott; Yap, Alpha S; Hogan, Benjamin M; Lagendijk, Anne Karine.

Development ; 149(23)2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36314606

4.

A bigger picture: classical cadherins and the dynamic actin cytoskeleton.

Ratheesh, Aparna; Yap, Alpha S.

Nat Rev Mol Cell Biol ; 13(10): 673-9, 2012 10.

Artigo em Inglês | MEDLINE | ID: mdl-22931853

5.

Enhanced RhoA signalling stabilizes E-cadherin in migrating epithelial monolayers.

Gupta, Shafali; Duszyc, Kinga; Verma, Suzie; Budnar, Srikanth; Liang, Xuan; Gomez, Guillermo A; Marcq, Philippe; Noordstra, Ivar; Yap, Alpha S.

J Cell Sci ; 134(17)2021 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-34368835

6.

Organizing junctions at the cell-cell interface.

Akhmanova, Anna; Yap, Alpha S.

Cell ; 135(5): 791-3, 2008 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-19041742

7.

Modular transient nanoclustering of activated ß2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies.

Gormal, Rachel S; Padmanabhan, Pranesh; Kasula, Ravikiran; Bademosi, Adekunle T; Coakley, Sean; Giacomotto, Jean; Blum, Ailisa; Joensuu, Merja; Wallis, Tristan P; Lo, Harriet P; Budnar, Srikanth; Rae, James; Ferguson, Charles; Bastiani, Michele; Thomas, Walter G; Pardon, Els; Steyaert, Jan; Yap, Alpha S; Goodhill, Geoffrey J; Hilliard, Massimo A; Parton, Robert G; Meunier, Frédéric A.

Proc Natl Acad Sci U S A ; 117(48): 30476-30487, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33214152

8.

Endocytosis, cadherins and tissue dynamics.

Katsuno-Kambe, Hiroko; Yap, Alpha S.

Traffic ; 21(3): 268-273, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31912628

9.

Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell-matrix adhesion.

Wee, Kenneth; Hediyeh-Zadeh, Soroor; Duszyc, Kinga; Verma, Suzie; N Nanavati, Bageshri; Khare, Satyajeet; Varma, Amrita; Daly, Roger J; Yap, Alpha S; Davis, Melissa J; Budnar, Srikanth.

J Cell Sci ; 133(13)2020 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-32467325

10.

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers.

Balasubramaniam, Lakshmi; Doostmohammadi, Amin; Saw, Thuan Beng; Narayana, Gautham Hari Narayana Sankara; Mueller, Romain; Dang, Tien; Thomas, Minnah; Gupta, Shafali; Sonam, Surabhi; Yap, Alpha S; Toyama, Yusuke; Mège, René-Marc; Yeomans, Julia M; Ladoux, Benoît.

Nat Mater ; 20(8): 1156-1166, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-33603188

11.

Caveolin-1 influences epithelial collective cell migration via FMNL2 formin.

Katsuno-Kambe, Hiroko; Parton, Robert G; Yap, Alpha S; Teo, Jessica L.

Biol Cell ; 113(2): 107-117, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33169848

12.

Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis.

Bonfim-Melo, Alexis; Duszyc, Kinga; Gomez, Guillermo A; Yap, Alpha S.

Eur Phys J E Soft Matter ; 45(1): 9, 2022 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-35076820

13.

Anillin: The First Proofreading-like Scaffold?

Morris, Richard G; Husain, Kabir B; Budnar, Srikanth; Yap, Alpha S.

Bioessays ; 42(10): e2000055, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32735042

14.

The importance of character development in scientific research.

Schwartz, Martin A; Yap, Alpha S.

J Cell Sci ; 136(13)2023 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-37403645

15.

The membrane environment of cadherin adhesion receptors: a working hypothesis.

Teo, Jessica L; Parton, Robert G; Yap, Alpha S.

Biochem Soc Trans ; 47(4): 985-995, 2019 08 30.

Artigo em Inglês | MEDLINE | ID: mdl-31278153

16.

Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation.

Niessen, Carien M; Leckband, Deborah; Yap, Alpha S.

Physiol Rev ; 91(2): 691-731, 2011 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-21527735

17.

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion.

Bracken, Cameron P; Li, Xiaochun; Wright, Josephine A; Lawrence, David M; Pillman, Katherine A; Salmanidis, Marika; Anderson, Matthew A; Dredge, B Kate; Gregory, Philip A; Tsykin, Anna; Neilsen, Corine; Thomson, Daniel W; Bert, Andrew G; Leerberg, Joanne M; Yap, Alpha S; Jensen, Kirk B; Khew-Goodall, Yeesim; Goodall, Gregory J.

EMBO J ; 33(18): 2040-56, 2014 Sep 17.

Artigo em Inglês | MEDLINE | ID: mdl-25069772

18.

Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury.

Coburn, Luke; Lopez, Hender; Schouwenaar, Irin-Maya; Yap, Alpha S; Lobaskin, Vladimir; Gomez, Guillermo A.

Phys Biol ; 15(2): 024001, 2018 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-29091048

19.

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions.

Priya, Rashmi; Gomez, Guillermo A; Budnar, Srikanth; Acharya, Bipul R; Czirok, Andras; Yap, Alpha S; Neufeld, Zoltan.

PLoS Comput Biol ; 13(3): e1005411, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-28273072

20.

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Humphrey, Emily S; Su, Shih-Ping; Nagrial, Adnan M; Hochgräfe, Falko; Pajic, Marina; Lehrbach, Gillian M; Parton, Robert G; Yap, Alpha S; Horvath, Lisa G; Chang, David K; Biankin, Andrew V; Wu, Jianmin; Daly, Roger J.

Mol Cell Proteomics ; 15(8): 2671-85, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27259358

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