Detalhe da pesquisa
1.
G-Clamp Heterocycle Modification Containing Interstrand Photo-Cross-Linker to Capture Intracellular MicroRNA Targets.
J Am Chem Soc
; 146(18): 12778-12789, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38679963
2.
Design and Synthesis of Pleuromutilin Derivatives as Antibacterial Agents Using Quantitative Structure-Activity Relationship Model.
Int J Mol Sci
; 25(4)2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38396934
3.
Antibiotic resistance and drug modification: Synthesis, characterization and bioactivity of newly modified potent pleuromutilin derivatives with a substituted piperazine moiety.
Bioorg Chem
; 132: 106353, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669358
4.
The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres.
Int J Mol Sci
; 24(19)2023 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37834176
5.
Efficacy of the Antimalarial MMV390048 against Babesia Infection Reveals Phosphatidylinositol 4-Kinase as a Druggable Target for Babesiosis.
Antimicrob Agents Chemother
; 66(9): e0057422, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924942
6.
A new pleuromutilin candidate with potent antibacterial activity against Pasteurella multocida.
Microb Pathog
; 127: 202-207, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529392
7.
A Validated HPLC-MS/MS Assay for 14-O-[(4,6-Diaminopyrimidine-2-yl)thioacetyl] Mutilin in Biological Samples and Its Pharmacokinetic, Distribution and Excretion via Urine and Feces in Rats.
Molecules
; 24(4)2019 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30813235
8.
Antibacterial activity and pharmacokinetic profile of a promising antibacterial agent: 14-O-[(4-Amino-6-hydroxy-pyrimidine-2-yl)thioacetyl] mutilin.
Pharmacol Res
; 129: 424-431, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133214
9.
Synthesis and antibacterial activities of novel pleuromutilin derivatives.
Arch Pharm (Weinheim)
; 351(9): e1800155, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30058185
10.
Synthesis and Biological Activity Evaluation of Novel Heterocyclic Pleuromutilin Derivatives.
Molecules
; 22(6)2017 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28617344
11.
Synthesis and Pharmacological Evaluation of Novel Pleuromutilin Derivatives with Substituted Benzimidazole Moieties.
Molecules
; 21(11)2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27834819
12.
Review of Platensimycin and Platencin: Inhibitors of ß-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH).
Molecules
; 20(9): 16127-41, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26404223
13.
In vivo efficacy and toxicity studies of a novel antibacterial agent: 14-o-[(2-amino-1,3,4-thiadiazol-5-yl)thioacetyl] mutilin.
Molecules
; 20(4): 5299-312, 2015 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25812151
14.
Synthesis and biological evaluation of new pleuromutilin derivatives as antibacterial agents.
Molecules
; 19(11): 19050-65, 2014 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415471
15.
Safety and efficacy evaluation of halicin as an effective drug for inhibiting intestinal infections.
Front Pharmacol
; 15: 1389293, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38783954
16.
Comparison of gut microbiota immunity and pathology in specific-pathogen-free chickens with glandular and muscular gastritis using different methods.
Front Vet Sci
; 11: 1343768, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38887537
17.
GLORI for absolute quantification of transcriptome-wide m6A at single-base resolution.
Nat Protoc
; 19(4): 1252-1287, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253658
18.
Synthesis and evaluation of novel pleuromutilin derivatives targeting the 50S ribosomal subunit for antibacterial ability.
Eur J Med Chem
; 262: 115882, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37879170
19.
Anti-methicillin-resistant Staphylococcus aureus activity and safety evaluation of 14-O-[(5-ethoxycarbonyl-4,6-dimethylpyrimidine-2-yl) thioacetyl] mutilin (EDT).
Sci Rep
; 13(1): 15267, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37709940
20.
Novel pyridinium cationic pleuromutilin analogues overcoming bacterial multidrug resistance.
Eur J Med Chem
; 251: 115269, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36924667