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1.
Opt Express ; 32(3): 3946-3958, 2024 Jan 29.
Artigo em Inglês | MEDLINE | ID: mdl-38297604

RESUMO

We demonstrate an intriguing transmittance contrast in a glide-symmetric square-lattice photonic crystal waveguide with a 90-degree sharp bend. The glide-symmetry gives rise to a degeneracy point in the band structure and separates a high-frequency and a low-frequency band. Previously, a similar large transmittance contrast between these two bands has been observed in glide-symmetric triangular- or honeycomb-lattice photonic crystals without inversion symmetry, and this phenomenon has been attributed to the valley-photonic effect. In this study, we demonstrate the first example of this phenomenon in square-lattice photonic crystals, which do not possess the valley effect. Our result sheds new light onto unexplored properties of glide-symmetric waveguides. We show that this phenomenon is related to the spatial distribution of circular polarization singularities in glide-symmetric waveguides. This work expands the possible designs of low-loss photonic circuits and provides a new understanding of light transmission via sharp bends in photonic crystal waveguides.

2.
Opt Express ; 32(2): 1802-1824, 2024 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-38297724

RESUMO

It has been well established that photonic crystal nanocavities with wavelength sized mode volume enable various integrable photonic devices with extremely small consumption energy and small footprint. In this study, we explore the possibility of non-volatile functionalities employing photonic crystal nanocavities and phase change material, Ge2Sb2Te5 (GST). Recently, non-volatile photonic devices based on GST have attracted significant interest and are expected to enable energy-efficient photonic processing, especially for optical computing. However, the device size and the area of GST in previous studies have been rather large. Here, we propose and fabricate Si photonic crystal nanocavities on which submicron-square GST patterns are selectively loaded. Because of the strong light confinement, extremely small area of GST is sufficient to manipulate the cavity mode. We have succeeded to fabricate 30-nm-thick and several-100nm-square GST blocks patterned at the center of photonic crystal cavity with a high alignment accuracy. We confirmed that the resonant wavelength and Q-factor of cavity modes are controlled by the phase change of GST. Moreover, cavity formation controlled by submicron-sized GST is also demonstrated by GST-loaded photonic-crystal line-defect waveguides. Our approach in which we place sub-micron-sized GST inside a photonic crystal nanocavity is promising for realizing extremely energy-efficient non-volatile integrable photonic devices, such as switches, modulators, memories, and reconfigurable novel devices.

3.
J Inherit Metab Dis ; 44(3): 718-727, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33332637

RESUMO

X-linked adrenoleukodystrophy (X-ALD) is a severe inherited metabolic disease with cerebral inflammatory demyelination and abnormal accumulation of very long chain fatty acid (VLCFA) in tissues, especially the brain. At present, bone marrow transplantation (BMT) at an early stage of the disease is the only effective treatment for halting disease progression, but the underlying mechanism of the treatment has remained unclear. Here, we transplanted GFP-expressing wild-type (WT) or Abcd1-deficient (KO) bone marrow cells into recipient KO mice, which enabled tracking of the donor GFP+ cells in the recipient mice. Both the WT and KO donor cells were equally distributed throughout the brain parenchyma, and displayed an Iba1-positive, GFAP- and Olig2-negative phenotype, indicating that most of the donor cells were engrafted as microglia-like cells. They constituted approximately 40% of the Iba1-positive cells. Unexpectedly, no decrease of VLCFA in the cerebrum was observed when WT bone marrow cells were transplanted into KO mice. Taken together, murine study suggests that bone marrow-derived microglia-like cells engrafted in the cerebrum of X-ALD patients suppress disease progression without evidently reducing the amount of VLCFA in the cerebrum.


Assuntos
Membro 1 da Subfamília D de Transportadores de Cassetes de Ligação de ATP/deficiência , Adrenoleucodistrofia/terapia , Transplante de Medula Óssea , Encéfalo/metabolismo , Membro 1 da Subfamília D de Transportadores de Cassetes de Ligação de ATP/genética , Adrenoleucodistrofia/metabolismo , Animais , Proteínas de Ligação ao Cálcio/metabolismo , Células Cultivadas , Proteína Glial Fibrilar Ácida/metabolismo , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Knockout , Proteínas dos Microfilamentos/metabolismo , Fator de Transcrição 2 de Oligodendrócitos/metabolismo
4.
Phys Rev Lett ; 125(5): 053902, 2020 Jul 31.
Artigo em Inglês | MEDLINE | ID: mdl-32794854

RESUMO

We demonstrate by breaking the C_{6} symmetry for higher-order at-Γ bound states in the continuum (BICs) with topological charge -2 in photonic crystals (i) deterministic generation of off-Γ BICs from the at-Γ BIC and (ii) a variety of pair-creation and annihilation processes of circularly polarized states with opposite topological charges and the same handedness. To explain these phenomena, we introduce the handedness-wise topological charge quantized to a half-integer. The handedness-wise charge gives a unified picture of various phenomena involving BICs and circularly polarized states.

5.
Nano Lett ; 18(2): 916-920, 2018 02 14.
Artigo em Inglês | MEDLINE | ID: mdl-29373028

RESUMO

We theoretically study current-induced orbital magnetization in a chiral crystal. This phenomenon is an orbital version of the Edelstein effect. We propose an analogy between the current-induced orbital magnetization and an Ampère field in a solenoid in classical electrodynamics. To quantify this effect, we define a dimensionless parameter from the response coefficients relating a current density with an orbital magnetization. This dimensionless parameter can be regarded as a number of turns within a unit cell when the crystal is regarded as a solenoid, and it represents how "chiral" the crystal is. By focusing on the dimensionless parameter, one can design a band structure that realizes the induction of large orbital magnetization. In particular, a Weyl semimetal with all of the Weyl nodes close to the Fermi energy can have a large value for this dimensionless parameter, which can exceed that of a classical solenoid.

6.
Sci Rep ; 5: 12024, 2015 Jul 09.
Artigo em Inglês | MEDLINE | ID: mdl-26156643

RESUMO

We theoretically show that in a crystal with a helical lattice structure, orbital and spin magnetizations along a helical axis are induced by an electric current along the helical axis. We propose a simple tight-binding model for calculations, and the results can be generalized to any helical crystals. The induced magnetizations are opposite for right-handed and left-handed helices. The current-induced spin magnetization along the helical axis comes from a radial spin texture on the Fermi surface. This is in sharp contrast to Rashba systems where the induced spin magnetization is perpendicular to the applied current.

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