Research Progress on Photocatalytic CO2 Reduction Based on Perovskite Oxides.

Photocatalytic CO2 reduction to valuable fuels is a promising way to alleviate anthropogenic CO2 emissions and energy crises. Perovskite oxides have attracted widespread attention as photocatalysts for CO2 reduction by virtue of their high catalytic activity, compositional flexibility, bandgap adjustability, and good stability. In this review, the basic theory of photocatalysis and the mechanism of CO2 reduction over perovskite oxide are first introduced. Then, perovskite oxides' structures, properties, and preparations are presented. In detail, the research progress on perovskite oxides for photocatalytic CO2 reduction is discussed from five aspects: as a photocatalyst in its own right, metal cation doping at A and B sites of perovskite oxides, anion doping at O sites of perovskite oxides and oxygen vacancies, loading cocatalyst on perovskite oxides, and constructing heterojunction with other semiconductors. Finally, the development prospects of perovskite oxides for photocatalytic CO2 reduction are put forward. This article should serve as a useful guide for creating perovskite oxide-based photocatalysts that are more effective and reasonable.

Recent Development of Non-Contact Multi-Target Vital Sign Detection and Location Tracking Based on Metamaterial Leaky Wave Antennas.

Microwave radar sensors have been developed for non-contact monitoring of the health condition and location of targets, which will cause minimal discomfort and eliminate sanitation issues, especially in a pandemic situation. To this end, several radar sensor architectures and algorithms have been proposed to detect multiple targets at different locations. Traditionally, beamforming techniques incorporating phase shifters or mechanical rotors are utilized, which is relatively complex and costly. On the other hand, metamaterial (MTM) leaky wave antennas (LWAs) have a unique property of launching waves of different spectral components in different directions. This feature can be utilized to detect multiple targets at different locations to obtain their healthcare and location information accurately, without complex structure and high cost. To this end, this paper reviews the recent development of MTM LWA-based radar sensor architectures for vital sign detection and location tracking. The experimental results demonstrate the effectiveness of MTM vital sign radar compared with different radar sensor architectures.

Study on the method of compensation for the heading effect of the rate offset frequency laser inertial measurement unit.

For the rate offset frequency laser inertial measurement unit (IMU), the errors of its three attitude angles, laser gyroscope, and accelerometer are coupled, which will affect the initial alignment result of the IMU and will make the measurement results of the IMU at different positions and angles deviate from the truth value. Meanwhile, with the increase of tilt angle, the heading effect becomes more obvious, and the error value is distributed positively cosine with the heading angle. In order to ensure the adaptability of the IMU to various operating conditions, it is necessary to compensate for the heading effect. The contribution of each error source of IMU to the heading effect is theoretically studied in this paper. We present a new method for compensating for the heading effect of the rate offset frequency laser IMU, in which the normal drift error of the vertical direction laser gyroscope and the zero bias error of the accelerometer under the turntable coordinate system are compensated. Based on the above method, simulation analysis and test verification are carried out. The experimental results show that the compensation method has a remarkable effect. In the case of two horizontal attitude angles tilted 0.0873 rad and 5 min initial alignment, the error of the rate offset frequency laser IMU reduced from 5.02E-04 rad $({3}\sigma)$(3σ) to 1.45E-04 rad $({3}\sigma)$(3σ), and the accuracy increased by 71%. High-precision initial alignment is achieved, which can meet the requirements of high-precision engineering applications.

4-Deoxy-ε-Pyrromycinone: A Promising Drug/Lead Compound to Treat Tumors.

Background: Anthraquinone drugs are widely used in the treatment of tumors. However, multidrug resistance and severe cardiac toxicity limit its use, which have led to the discovery of new analogues. In this paper, 4-Deoxy-ε-pyrromycinone (4-Deo), belonging to anthraquinone compounds, was first been studied with the anti-tumor effects and the safety in vitro and in vivo as a new anti-tumor drug or lead compound. Methods: The quantitative analysis of 4-Deo was established by UV methodology. The anti-cancer effect of 4-Deo in vitro was evaluated by cytotoxicity experiments of H22, HepG2 and Caco2, and the anti-cancer mechanism was explored by cell apoptosis and cycle. The tumor-bearing mouse model was established by subcutaneous inoculation of H22 cells to evaluate the anti-tumor effect of 4-Deo in vivo. The safety of 4-Deo was verified by the in vitro safety experiments of healthy cells and the in vivo safety experiments of H22 tumor-bearing mice. Tumor tissue sections were labeled with CRT, HMGB1, IL-6 and CD115 to explore the preliminary anti-cancer mechanism by immunohistochemistry. Results: In vitro experiments demonstrated that 4-Deo could inhibit the growth of H22 by inducing cell necrosis and blocking cells in S phase, and 4-Deo has less damage to healthy cells. In vivo experiments showed that 4-Deo increased the positive area of CRT and HMGB1, which may inhibit tumor growth by triggering immunogenic cell death (ICD). In addition, 4-Deo reduced the positive area of CSF1R, and the anti-tumor effect may be achieved by blocking the transformation of tumor-associated macrophages (TAMs) to M2 phenotype. Conclusion: In summary, this paper demonstrated the promise of 4-Deo for cancer treatment in vitro and in vivo. This paper lays the foundation for the study of 4-Deo, which is beneficial for the further development anti-tumor drugs based on the lead compound of 4-Deo.

Nitric Oxide Improves Salt Tolerance of Cyclocarya paliurus by Regulating Endogenous Glutathione Level and Antioxidant Capacity.

Cyclocarya paliurus is commonly used to treat diabetes in China. However, the natural habitats of C. paliurus are typically affected by salt stress. Previous studies showed that nitric oxide (NO) level was related to salt tolerance of C. paliurus, and its synthesis was induced by exogenous hydrogen sulfide. However, the effects of different NO donors in alleviating the negative effect of salt stress are still unclear. In the present study, C. paliurus seedlings pretreated with three NO donors (S-nitroso-N-acetylpenicillamine, SNAP and S-nitrosoglutathione, GSNO and sodium nitroprusside, SNP) were exposed to salt stress, and then, the total biomass, chlorophyll fluorescence parameters, NO and glutathione levels, oxidative damage, and antioxidant enzyme activities were investigated. The results showed that pretreatment of NO donors maintained chlorophyll fluorescence and attenuated the loss of plant biomass under salt stress, and the best performance was observed in C. paliurus under SNP treatment. We also found that pretreatment of NO donors further increased the endogenous NO content and nitrate reductase (NR) activity compared with salt treatment. Moreover, pretreatment with NO donors, especially SNP, alleviated salt-induced oxidative damage, as indicated by lowered lipid peroxidation, through an enhanced antioxidant system including glutathione accumulation and increased antioxidant enzyme activities. The supply of NO donors is an interesting strategy for alleviating the negative effect of salt on C. paliurus. Our data provide new evidence contributing to the current understanding of NO-induced salt stress tolerance.