Detalhe da pesquisa
1.
Integrated analysis of multimodal single-cell data.
Cell
; 184(13): 3573-3587.e29, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34062119
2.
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.
Cell
; 183(6): 1479-1495.e20, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33171100
3.
Preclinical PK/PD modeling and human efficacious dose projection for a glucokinase activator in the treatment of diabetes.
J Pharmacokinet Pharmacodyn
; 41(2): 127-39, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24578187
4.
A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities.
Elife
; 122024 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305363
5.
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.
Proc Natl Acad Sci U S A
; 107(20): 9446-51, 2010 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20439741
6.
Single-cell immunology of SARS-CoV-2 infection.
Nat Biotechnol
; 40(1): 30-41, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931002
7.
Sources of inter-individual variability leading to significant changes in anti-PD-1 and anti-PD-L1 efficacy identified in mouse tumor models using a QSP framework.
Front Pharmacol
; 13: 1056365, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36545310
8.
Model-informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma.
CPT Pharmacometrics Syst Pharmacol
; 11(6): 687-697, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447014
9.
Oncogenic role of a developmentally regulated NTRK2 splice variant.
Sci Adv
; 8(40): eabo6789, 2022 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206341
10.
Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Elife
; 112022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511483
11.
A human cell atlas of fetal chromatin accessibility.
Science
; 370(6518)2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184180
12.
A human cell atlas of fetal gene expression.
Science
; 370(6518)2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184181
13.
Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.
Acta Neuropathol Commun
; 5(1): 39, 2017 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28532485
14.
Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer.
Mol Cancer Ther
; 13(8): 2104-15, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24928852
15.
Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape.
Nat Genet
; 50(9): 1203-1204, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30158685
16.
The development of a fully-integrated immune response model (FIRM) simulator of the immune response through integration of multiple subset models.
BMC Syst Biol
; 7: 95, 2013 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24074340
17.
A multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenance.
PLoS One
; 7(9): e44359, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970204
18.
A delayed nonlinear PBPK model for genistein dosimetry in rats.
Bull Math Biol
; 69(1): 93-117, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17024552
19.
Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
Am J Physiol Endocrinol Metab
; 291(5): E952-64, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16757547