Detalhe da pesquisa
1.
Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.
Br J Cancer
; 124(7): 1249-1259, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33473169
2.
Optimized Target Residence Time: Typeâ I1/2 Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R-Spine.
Angew Chem Int Ed Engl
; 56(19): 5363-5367, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28397331
3.
IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.
PLoS Med
; 13(12): e1002200, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27997540
4.
Chemokine cooperativity is caused by competitive glycosaminoglycan binding.
J Immunol
; 192(8): 3908-3914, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24639348
5.
ß-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.
J Biol Chem
; 288(10): 7169-81, 2013 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341447
6.
The bacterial lysate OM-85 engages Toll-like receptors 2 and 4 triggering an immunomodulatory gene signature in human myeloid cells.
Mucosal Immunol
; 17(3): 346-358, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447907
7.
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nat Commun
; 15(1): 482, 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38228616
8.
Amino Acid-Metabolizing Enzymes in Advanced High-Grade Serous Ovarian Cancer Patients: Value of Ascites as Biomarker Source and Role for IL4I1 and IDO1.
Cancers (Basel)
; 15(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765849
9.
Comparative biochemical kinase activity analysis identifies rivoceranib as a highly selective VEGFR2 inhibitor.
Cancer Chemother Pharmacol
; 91(6): 491-499, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148323
10.
Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.
Nat Commun
; 13(1): 1048, 2022 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217681
11.
Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020.
Front Oncol
; 12: 953013, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36185300
12.
A theoretical entropy score as a single value to express inhibitor selectivity.
BMC Bioinformatics
; 12: 94, 2011 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21486481
13.
Identification of a novel allosteric binding site in the CXCR2 chemokine receptor.
Mol Pharmacol
; 80(6): 1108-18, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21948388
14.
beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling.
FASEB J
; 24(4): 1205-17, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19940259
15.
Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Bioorg Med Chem Lett
; 21(1): 97-101, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145740
16.
Pharmacological validation of TDO as a target for Parkinson's disease.
FEBS J
; 288(14): 4311-4331, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33471408
17.
MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
Leukemia
; 35(12): 3394-3405, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34007050
18.
Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X
; 4: 100014, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647818
19.
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
SLAS Discov
; 25(9): 1018-1025, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32418491
20.
Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites.
Oncotarget
; 11(49): 4570-4581, 2020 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33346216