Detalhe da pesquisa
1.
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents.
Proc Natl Acad Sci U S A
; 113(19): 5388-93, 2016 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27118832
2.
Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X.
Molecules
; 24(21)2019 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690062
3.
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.
Bioorg Med Chem Lett
; 28(21): 3454-3457, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30262428
4.
Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.
Bioorg Med Chem Lett
; 27(14): 3196-3200, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28558969
5.
One drug for two targets: Biological evaluation of antiretroviral agents endowed with antiproliferative activity.
Bioorg Med Chem Lett
; 27(11): 2502-2505, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408224
6.
SRC family kinase inhibition through a new pyrazolo[3,4-d]pyrimidine derivative as a feasible approach for glioblastoma treatment.
J Cell Biochem
; 116(5): 856-63, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25521525
7.
2-Aminothiazolones as anti-HIV agents that act as gp120-CD4 inhibitors.
Antimicrob Agents Chemother
; 58(6): 3043-52, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24614386
8.
Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity.
Bioorg Med Chem Lett
; 24(23): 5525-9, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25455183
9.
Noncanonical-NF-κB activation and DDX3 inhibition reduces the HIV-1 reservoir by elimination of latently infected cells ex-vivo.
Microbiol Spectr
; 12(1): e0318023, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051053
10.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
Bioorg Med Chem Lett
; 22(17): 5579-83, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853993
11.
The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma.
Biomedicines
; 10(3)2022 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35327462
12.
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.
Bioorg Med Chem Lett
; 21(19): 5928-33, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21856155
13.
Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
Eur J Med Chem
; 223: 113653, 2021 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34161866
14.
Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models.
Cancers (Basel)
; 13(21)2021 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771731
15.
Synthesis and Antiproliferative Activity of Nitric Oxide-Donor Largazole Prodrugs.
ACS Med Chem Lett
; 11(5): 846-851, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435394
16.
DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins.
Eur J Med Chem
; 200: 112319, 2020 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446036
17.
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains.
Int J Antimicrob Agents
; 55(3): 105865, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31866465
18.
DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection.
J Med Chem
; 62(5): 2333-2347, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30721061
19.
Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach .
J Med Chem
; 62(23): 10833-10847, 2019 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31729878
20.
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor.
Cancers (Basel)
; 11(6)2019 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31248184