Detalhe da pesquisa
1.
Irisin deficiency exacerbates diet-induced insulin resistance and cardiac dysfunction in type II diabetes in mice.
Am J Physiol Cell Physiol
; 325(4): C1085-C1096, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37694285
2.
A structural and functional comparison between two recombinant human lubricin proteins: Recombinant human proteoglycan-4 (rhPRG4) vs ECF843.
Exp Eye Res
; 235: 109643, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37678729
3.
Inhibition of integrin alpha v/beta 5 mitigates the protective effect induced by irisin in hemorrhage.
Exp Mol Pathol
; 134: 104869, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37690529
4.
Quadruped Gait and Regulation of Apoptotic Factors in Tibiofemoral Joints following Intra-Articular rhPRG4 Injection in Prg4 Null Mice.
Int J Mol Sci
; 23(8)2022 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35457064
5.
The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes.
Int J Mol Sci
; 22(15)2021 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360761
6.
p38-Regulated/activated protein kinase plays a pivotal role in protecting heart against ischemia-reperfusion injury and preserving cardiac performance.
Am J Physiol Cell Physiol
; 317(3): C525-C533, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31291142
7.
Irisin promotes cardiac progenitor cell-induced myocardial repair and functional improvement in infarcted heart.
J Cell Physiol
; 234(2): 1671-1681, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30171682
8.
cAMP attenuates TGF-ß's profibrotic responses in osteoarthritic synoviocytes: involvement of hyaluronan and PRG4.
Am J Physiol Cell Physiol
; 315(3): C432-C443, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29898378
9.
Friction-Induced Mitochondrial Dysregulation Contributes to Joint Deterioration in Prg4 Knockout Mice.
Int J Mol Sci
; 18(6)2017 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28604608
10.
Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis.
Proc Natl Acad Sci U S A
; 110(15): 5852-7, 2013 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23530215
11.
Specific inhibition of HDAC4 in cardiac progenitor cells enhances myocardial repairs.
Am J Physiol Cell Physiol
; 307(4): C358-72, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24944198
12.
Irisin Preserves Cardiac Performance and Insulin Sensitivity in Response to Hemorrhage.
Pharmaceuticals (Basel)
; 15(10)2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36297305
13.
gp-91 mediates histone deacetylase inhibition-induced cardioprotection.
Biochim Biophys Acta
; 1803(7): 872-80, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20433879
14.
Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection.
Arthritis Rheum
; 62(8): 2382-91, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506144
15.
Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration.
Arthritis Res Ther
; 23(1): 241, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34521469
16.
Proteoglycan-4 regulates fibroblast to myofibroblast transition and expression of fibrotic genes in the synovium.
Arthritis Res Ther
; 22(1): 113, 2020 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404156
17.
Transgenic overexpression of active HDAC4 in the heart attenuates cardiac function and exacerbates remodeling in infarcted myocardium.
J Appl Physiol (1985)
; 125(6): 1968-1978, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30284520
18.
Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages.
Arthritis Res Ther
; 20(1): 192, 2018 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157934
19.
Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage After Destabilization of the Medial Meniscus in the Yucatan Minipig.
Am J Sports Med
; 45(7): 1512-1521, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129516
20.
Correction to: Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration.
Arthritis Res Ther
; 23(1): 276, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34715928