Detalhe da pesquisa
1.
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.
Nature
; 602(7897): 510-517, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35140399
2.
Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity.
Am J Hum Genet
; 109(12): 2210-2229, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36423637
3.
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.
Hum Mol Genet
; 31(17): 2845-2856, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35357426
4.
Rare germline deleterious variants increase susceptibility for lung cancer.
Hum Mol Genet
; 31(20): 3558-3565, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35717579
5.
Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms.
Am J Hum Genet
; 108(9): 1631-1646, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293285
6.
A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer.
Am J Hum Genet
; 108(10): 1852-1865, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34559995
7.
A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR.
Am J Hum Genet
; 108(9): 1611-1630, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34343493
8.
Contribution of Common Genetic Variants to Familial Aggregation of Disease and Implications for Sequencing Studies.
PLoS Genet
; 15(11): e1008490, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730655
9.
Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers.
Am J Epidemiol
; 190(6): 962-976, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33712835
10.
Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes.
Genome Res
; 28(11): 1621-1635, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333196
11.
Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma.
Hum Mol Genet
; 27(23): 4145-4156, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30060076
12.
Immune gene expression profiling reveals heterogeneity in luminal breast tumors.
Breast Cancer Res
; 21(1): 147, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31856876
13.
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers.
Hum Mol Genet
; 26(15): 3014-3027, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28854564
14.
Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.
BMC Genet
; 20(1): 59, 2019 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31315583
15.
Distinct Genomic Landscape of Lung Adenocarcinoma from Household Use of Smoky Coal.
Am J Respir Crit Care Med
; 208(6): 733-736, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406454
16.
Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.
Gut
; 67(3): 521-533, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634199
17.
An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.
Proteomics
; 16(3): 417-26, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26553150
18.
Integrative genomics analysis of genes with biallelic loss and its relation to the expression of mRNA and micro-RNA in esophageal squamous cell carcinoma.
BMC Genomics
; 16(1): 732, 2015 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26409826
19.
Single-cell profiling of MC1R-inhibited melanocytes.
Pigment Cell Melanoma Res
; 37(2): 291-308, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972124
20.
mSigSDK - private, at scale, computation of mutation signatures.
ArXiv
; 2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38327678