Detalhe da pesquisa
1.
A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects.
Acta Pharmacol Sin
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38844788
2.
Establishment of a mouse model of cancer cachexia with spleen deficiency syndrome and the effects of atractylenolide I.
Acta Pharmacol Sin
; 41(2): 237-248, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31341256
3.
Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-α.
Acta Pharmacol Sin
; 39(3): 415-424, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29119969
4.
Corylifol A ameliorates muscle atrophy by inhibiting TAOK1/p38-MAPK/FoxO3 pathway in cancer cachexia.
J Cachexia Sarcopenia Muscle
; 14(5): 2098-2113, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439183
5.
Carnosol ameliorated cancer cachexia-associated myotube atrophy by targeting P5CS and its downstream pathways.
Front Pharmacol
; 14: 1291194, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38249348
6.
Alantolactone ameliorates cancer cachexia-associated muscle atrophy mainly by inhibiting the STAT3 signaling pathway.
Phytomedicine
; 95: 153858, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861585
7.
Carnosol attenuated atrophy of C2C12 myotubes induced by tumour-derived exosomal miR-183-5p through inhibiting Smad3 pathway activation and keeping mitochondrial respiration.
Basic Clin Pharmacol Toxicol
; 131(6): 500-513, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150451
8.
Retraction Notice to: Long Noncoding RNA OIP5-AS1 Promotes the Progression of Liver Hepatocellular Carcinoma via Regulating the hsa-miR-26a-3p/EPHA2 Axis.
Mol Ther Nucleic Acids
; 30: 324, 2022 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36381584
9.
Long Noncoding RNA OIP5-AS1 Promotes the Progression of Liver Hepatocellular Carcinoma via Regulating the hsa-miR-26a-3p/EPHA2 Axis.
Mol Ther Nucleic Acids
; 21: 229-241, 2020 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32585630
10.
SiBaoChongCao exhibited anti-fatigue activities and ameliorated cancer cachexia in mice.
RSC Adv
; 9(30): 17440-17456, 2019 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35519898
11.
Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition.
Free Radic Biol Med
; 45(5): 627-35, 2008 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18582559
12.
Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma.
Acta Pharmacol Sin
; 29(12): 1467-77, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19026166
13.
MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.
Mol Cancer Ther
; 6(11): 3059-70, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18025289
14.
Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities.
Eur J Med Chem
; 126: 1083-1106, 2017 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039836
15.
Expression and purification of the catalytic domain of human vascular endothelial growth factor receptor 2 for inhibitor screening.
Biochim Biophys Acta
; 1722(3): 254-61, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15715968
16.
TKI-31 inhibits angiogenesis by combined suppression signaling pathway of VEGFR2 and PDGFRbeta.
Cancer Biol Ther
; 5(3): 323-30, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16575201
17.
Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells.
Br J Pharmacol
; 148(6): 741-51, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16715123
18.
Antimetastatic effect of salvicine on human breast cancer MDA-MB-435 orthotopic xenograft is closely related to Rho-dependent pathway.
Clin Cancer Res
; 11(9): 3455-64, 2005 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15867248
19.
Evaluation of active recombinant catalytic domain of human ErbB-2 tyrosine kinase, and suppression of activity by a naturally derived inhibitor, ZH-4B.
Biochim Biophys Acta
; 1673(3): 186-93, 2004 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15279890
20.
In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects.
Cancer Biol Ther
; 4(10): 1125-32, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16096368