Detalhe da pesquisa
1.
Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
Gastroenterology
; 163(6): 1593-1612, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948109
2.
Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling.
Am J Physiol Gastrointest Liver Physiol
; 323(4): G375-G386, 2022 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36098401
3.
Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice.
Proc Natl Acad Sci U S A
; 115(10): E2338-E2347, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463717
4.
Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain.
Arch Biochem Biophys
; 601: 121-32, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26906074
5.
Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains.
J Muscle Res Cell Motil
; 36(6): 447-61, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668058
6.
FRET study of the structural and kinetic effects of PKC phosphomimetic cardiac troponin T mutants on thin filament regulation.
Arch Biochem Biophys
; 550-551: 1-11, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24708997
7.
Tumor Cell-Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer.
Cancer Res
; 84(8): 1320-1332, 2024 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285896
8.
Structural dynamics of C-domain of cardiac troponin I protein in reconstituted thin filament.
J Biol Chem
; 287(10): 7661-74, 2012 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22207765
9.
Structural and kinetic effects of hypertrophic cardiomyopathy related mutations R146G/Q and R163W on the regulatory switching activity of rat cardiac troponin I.
Arch Biochem Biophys
; 535(1): 56-67, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246786
10.
Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer.
Cancer Res Commun
; 3(7): 1224-1236, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37448553
11.
Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer.
Cancer Discov
; 13(6): 1428-1453, 2023 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36946782
12.
DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer.
Clin Cancer Res
; 28(9): 1948-1965, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135840
13.
Molecular and Functional Effects of a Splice Site Mutation in the MYL2 Gene Associated with Cardioskeletal Myopathy and Early Cardiac Death in Infants.
Front Physiol
; 7: 240, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378946
14.
Novel familial dilated cardiomyopathy mutation in MYL2 affects the structure and function of myosin regulatory light chain.
FEBS J
; 282(12): 2379-93, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825243
15.
Quantitative determination of rhein in human plasma by liquid chromatography-negative electrospray ionization tandem mass/mass spectrometry and the application in a pharmacokinetic study.
J Pharm Biomed Anal
; 57: 19-25, 2012 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21945452
16.
A critical role of CCR7 in invasiveness and metastasis of SW620 colon cancer cell in vitro and in vivo.
Cancer Biol Ther
; 7(7): 1037-43, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18437055