Detalhe da pesquisa
1.
Prolonged Differentiation of Neuron-Astrocyte Co-Cultures Results in Emergence of Dopaminergic Neurons.
Int J Mol Sci
; 24(4)2023 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835019
2.
Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors.
Bioorg Med Chem Lett
; 52: 128406, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34624491
3.
The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish.
Toxicol Appl Pharmacol
; 407: 115249, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32979392
4.
Discovery of quinoline-based irreversible BTK inhibitors.
Bioorg Med Chem Lett
; 30(14): 127261, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32527559
5.
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Arch Toxicol
; 94(12): 4173-4196, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886187
6.
Is current risk assessment of non-genotoxic carcinogens protective?
Crit Rev Toxicol
; 48(6): 500-511, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29745287
7.
Head skeleton malformations in zebrafish (Danio rerio) to assess adverse effects of mixtures of compounds.
Arch Toxicol
; 92(12): 3549-3564, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30288550
8.
Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile.
J Pharmacol Exp Ther
; 363(2): 240-252, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882879
9.
A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.
Arch Toxicol
; 89(12): 2413-27, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25270620
10.
In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals.
Arch Toxicol
; 88(4): 1023-34, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24390151
11.
Dose addition in mixtures of compounds with dissimilar endocrine modes of action in in vitro receptor activation assays and the zebrafish sexual development test.
Food Chem Toxicol
; 184: 114432, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38176580
12.
Transferability and reproducibility of exposed air-liquid interface co-culture lung models.
NanoImpact
; 31: 100466, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37209722
13.
Novel ATP competitive MK2 inhibitors with potent biochemical and cell-based activity throughout the series.
Bioorg Med Chem Lett
; 22(1): 613-8, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22119462
14.
Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
Arch Toxicol
; 86(11): 1717-27, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22710402
15.
Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action.
Environ Health Perspect
; 130(4): 47003, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35394809
16.
An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials.
NanoImpact
; 28: 100439, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36402283
17.
Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.
Bioorg Med Chem Lett
; 21(12): 3823-7, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21565498
18.
Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Environ Mol Mutagen
; 62(4): 252-264, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33620775
19.
Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Food Chem Toxicol
; 147: 111855, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189884
20.
Developmental Neurotoxicity of Environmentally Relevant Pharmaceuticals and Mixtures Thereof in a Zebrafish Embryo Behavioural Test.
Int J Environ Res Public Health
; 18(13)2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34206423