Detalhe da pesquisa
1.
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Pharmacol Rev
; 75(6): 1233-1318, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586884
2.
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.
J Biol Chem
; 299(12): 105475, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981208
3.
The Tat inhibitor didehydro-cortistatin A suppresses SIV replication and reactivation.
FASEB J
; 33(7): 8280-8293, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31021670
4.
Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.
Nucleic Acids Res
; 45(14): 8596-8608, 2017 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28591827
5.
Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
Proc Natl Acad Sci U S A
; 113(2): 326-31, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26715749
6.
Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.
Antimicrob Agents Chemother
; 60(4): 2195-208, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26810656
7.
Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts.
Phys Chem Chem Phys
; 18(8): 5819-31, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26489725
8.
Elucidating a relationship between conformational sampling and drug resistance in HIV-1 protease.
Biochemistry
; 52(19): 3278-88, 2013 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23566104
9.
Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates.
Mol Microbiol
; 86(4): 971-87, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970855
10.
Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915.
Eur J Med Chem
; 258: 115582, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421886
11.
Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant.
Biochemistry
; 51(40): 7813-5, 2012 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23009326
12.
Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs.
J Ind Microbiol Biotechnol
; 39(10): 1523-32, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22752793
13.
Identification of potent small molecule inhibitors of SARS-CoV-2 entry.
SLAS Discov
; 27(1): 8-19, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058179
14.
Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.
J Med Chem
; 63(24): 15639-15654, 2020 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33289551
15.
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Cell Chem Biol
; 27(10): 1272-1284.e4, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763139
16.
Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1.
Structure
; 27(1): 66-77.e5, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30416039
17.
Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat.
mBio
; 10(1)2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30723126
18.
Advances in Orphan Nuclear Receptor Pharmacology: A New Era in Drug Discovery.
ACS Pharmacol Transl Sci
; 1(2): 134-137, 2018 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32219209
19.
Defining a conformational ensemble that directs activation of PPARγ.
Nat Commun
; 9(1): 1794, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29728618
20.
Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.
Structure
; 25(10): 1506-1518.e4, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28890360