Detalhe da pesquisa
1.
New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis.
Arch Toxicol
; 90(6): 1449-58, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238291
2.
Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes.
Arch Toxicol
; 90(5): 1103-15, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26104854
3.
Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans.
Chem Res Toxicol
; 28(10): 1936-48, 2015 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26360787
4.
Classification of hepatotoxicants using HepG2 cells: A proof of principle study.
Chem Res Toxicol
; 27(3): 433-42, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24437676
5.
Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks.
Mutagenesis
; 29(1): 17-26, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24280081
6.
Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells.
Part Fibre Toxicol
; 11: 4, 2014 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24438343
7.
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Carcinogenesis
; 34(6): 1393-402, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393228
8.
Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle.
Am J Physiol Renal Physiol
; 302(8): F905-16, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22262483
9.
'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.
Toxicol Appl Pharmacol
; 259(3): 320-8, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22285215
10.
Benzo[a]pyrene-induced changes in microRNA-mRNA networks.
Chem Res Toxicol
; 25(4): 838-49, 2012 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22316170
11.
Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity.
Mutagenesis
; 27(6): 645-52, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22914676
12.
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.
Arch Toxicol
; 86(11): 1703-15, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23052194
13.
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Arch Toxicol
; 86(9): 1399-411, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22484513
14.
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.
Arch Toxicol
; 86(11): 1741-51, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22760423
15.
An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
BMC Genomics
; 12: 251, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21599895
16.
Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.
Toxicol Appl Pharmacol
; 250(2): 96-107, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20970440
17.
Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures.
Toxicol Appl Pharmacol
; 251(2): 110-8, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21192963
18.
A lyophilized red grape pomace containing proanthocyanidin-rich dietary fiber induces genetic and metabolic alterations in colon mucosa of female C57BL/6J mice.
J Nutr
; 141(9): 1597-604, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775529
19.
Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study.
Environ Health
; 10: 85, 2011 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21975123
20.
Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans.
Mol Carcinog
; 48(8): 685-91, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19274671