Detalhe da pesquisa
1.
Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes.
Arch Toxicol
; 90(5): 1103-15, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26104854
2.
Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans.
Chem Res Toxicol
; 28(10): 1936-48, 2015 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26360787
3.
Classification of hepatotoxicants using HepG2 cells: A proof of principle study.
Chem Res Toxicol
; 27(3): 433-42, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24437676
4.
Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks.
Mutagenesis
; 29(1): 17-26, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24280081
5.
'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.
Toxicol Appl Pharmacol
; 259(3): 320-8, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22285215
6.
Benzo[a]pyrene-induced changes in microRNA-mRNA networks.
Chem Res Toxicol
; 25(4): 838-49, 2012 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22316170
7.
Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity.
Mutagenesis
; 27(6): 645-52, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22914676
8.
Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.
Toxicol Appl Pharmacol
; 250(2): 96-107, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20970440
9.
Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study.
Environ Health
; 10: 85, 2011 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21975123
10.
Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans.
Mol Carcinog
; 48(8): 685-91, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19274671
11.
Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.
Drug Metab Dispos
; 37(6): 1305-11, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19251822
12.
Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake.
Br J Nutr
; 101(9): 1295-9, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19434801
13.
Genomic analysis suggests higher susceptibility of children to air pollution.
Carcinogenesis
; 29(5): 977-83, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18332047
14.
Multiplex genotyping as a biomarker for susceptibility to carcinogenic exposure in the FLEHS biomonitoring study.
Cancer Epidemiol Biomarkers Prev
; 17(8): 1902-12, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18708379
15.
Transcriptome analysis in peripheral blood of humans exposed to environmental carcinogens: a promising new biomarker in environmental health studies.
Environ Health Perspect
; 116(11): 1519-25, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19057705
16.
Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices.
Mutagenesis
; 23(6): 491-9, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18711122
17.
Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach.
J Nutr Biochem
; 19(3): 139-57, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17651960
18.
Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation.
Carcinogenesis
; 28(12): 2632-40, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17690111
19.
Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers.
Cancer Epidemiol Biomarkers Prev
; 15(4): 624-9, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16614101
20.
Application of four dyes in gene expression analyses by microarrays.
BMC Genomics
; 6: 101, 2005 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16042794