Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Control of T cell antigen reactivity via programmed TCR downregulation.

Gallegos, Alena M; Xiong, Huizhong; Leiner, Ingrid M; Susac, Boze; Glickman, Michael S; Pamer, Eric G; van Heijst, Jeroen W J.

Nat Immunol ; 17(4): 379-86, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26901151

2.

Radical host-specific therapies for TB.

van Heijst, Jeroen W J; Pamer, Eric G.

Cell ; 153(3): 507-8, 2013 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-23622234

3.

Adherence Affects Monocyte Innate Immune Function and Metabolic Reprogramming after Lipopolysaccharide Stimulation In Vitro.

Otto, Natasja A; Butler, Joe M; Ramirez-Moral, Ivan; van Weeghel, Michel; van Heijst, Jeroen W J; Scicluna, Brendon P; Houtkooper, Riekelt H; de Vos, Alex F; van der Poll, Tom.

J Immunol ; 206(4): 827-838, 2021 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-33408258

4.

Association of Myeloid Liver Kinase B1 Depletion With a Reduction in Alveolar Macrophage Numbers and an Impaired Host Defense During Gram-Negative Pneumonia.

Otto, Natasja A; de Vos, Alex F; van Heijst, Jeroen W J; Roelofs, Joris J T H; van der Poll, Tom.

J Infect Dis ; 225(7): 1284-1295, 2022 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-32648919

5.

Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis.

Otto, Natasja A; Pereverzeva, Liza; Leopold, Valentine; Ramirez-Moral, Ivan; Roelofs, Joris J T H; van Heijst, Jeroen W J; de Vos, Alex F; van der Poll, Tom.

Mediators Inflamm ; 2021: 9958281, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34393650

6.

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.

Ates, Louis S; Sayes, Fadel; Frigui, Wafa; Ummels, Roy; Damen, Merel P M; Bottai, Daria; Behr, Marcel A; van Heijst, Jeroen W J; Bitter, Wilbert; Majlessi, Laleh; Brosch, Roland.

PLoS Pathog ; 14(6): e1007139, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29912964

7.

Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model.

Yang, Jack; van 't Veer, Cornelis; Roelofs, Joris J T H; van Heijst, Jeroen W J; de Vos, Alex F; McCrae, Keith R; Revenko, Alexey S; Crosby, Jeff; van der Poll, Tom.

Am J Physiol Lung Cell Mol Physiol ; 316(1): L187-L196, 2019 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-30358441

8.

Converging evolution leads to near maximal junction diversity through parallel mechanisms in B and T cell receptors.

Benichou, Jennifer I C; van Heijst, Jeroen W J; Glanville, Jacob; Louzoun, Yoram.

Phys Biol ; 14(4): 045003, 2017 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-28510537

9.

Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia.

Anas, Adam A; de Vos, Alex F; Hoogendijk, Arie J; van Lieshout, Miriam H P; van Heijst, Jeroen W J; Florquin, Sandrine; Li, Zihai; van 't Veer, Cornelis; van der Poll, Tom.

J Pathol ; 238(1): 74-84, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26365983

10.

A gamma interferon independent mechanism of CD4 T cell mediated control of M. tuberculosis infection in vivo.

Gallegos, Alena M; van Heijst, Jeroen W J; Samstein, Miriam; Su, Xiaodi; Pamer, Eric G; Glickman, Michael S.

PLoS Pathog ; 7(5): e1002052, 2011 May.

Artigo em Inglês | MEDLINE | ID: mdl-21625591

11.

An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes.

van der Donk, Lieve E H; van der Spek, Jet; van Duivenvoorde, Tom; Ten Brink, Marieke S; Geijtenbeek, Teunis B H; Kuijl, Coenraad P; van Heijst, Jeroen W J; Ates, Louis S.

Biol Open ; 11(2)2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35229875

12.

Separate signaling events control TCR downregulation and T cell activation in primary human T cells.

van der Donk, Lieve E H; Ates, Louis S; van der Spek, Jet; Tukker, Laura M; Geijtenbeek, Teunis B H; van Heijst, Jeroen W J.

Immun Inflamm Dis ; 9(1): 223-238, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33350598

13.

Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity.

Ates, Louis S; Dippenaar, Anzaan; Sayes, Fadel; Pawlik, Alexandre; Bouchier, Christiane; Ma, Laurence; Warren, Robin M; Sougakoff, Wladimir; Majlessi, Laleh; van Heijst, Jeroen W J; Brossier, Florence; Brosch, Roland.

Genome Biol Evol ; 10(8): 1858-1874, 2018 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-30010947

14.

Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis.

van Heijst, Jeroen W J; Niessen, Hans W M; Musters, Rene J; van Hinsbergh, Victor W M; Hoekman, Klaas; Schalkwijk, Casper G.

Cancer Lett ; 241(2): 309-19, 2006 Sep 28.

Artigo em Inglês | MEDLINE | ID: mdl-16337338

15.

Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine.

van Heijst, Jeroen W J; Niessen, Hans W M; Hoekman, Klaas; Schalkwijk, Casper G.

Ann N Y Acad Sci ; 1043: 725-33, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16037299

16.

Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation.

van Heijst, Jeroen W J; Ceberio, Izaskun; Lipuma, Lauren B; Samilo, Dane W; Wasilewski, Gloria D; Gonzales, Anne Marie R; Nieves, Jimmy L; van den Brink, Marcel R M; Perales, Miguel A; Pamer, Eric G.

Nat Med ; 19(3): 372-7, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23435170

17.

Heterogeneous differentiation patterns of individual CD8+ T cells.

Gerlach, Carmen; Rohr, Jan C; Perié, Leïla; van Rooij, Nienke; van Heijst, Jeroen W J; Velds, Arno; Urbanus, Jos; Naik, Shalin H; Jacobs, Heinz; Beltman, Joost B; de Boer, Rob J; Schumacher, Ton N M.

Science ; 340(6132): 635-9, 2013 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-23493421

18.

The descent of memory T cells.

Gerlach, Carmen; van Heijst, Jeroen W J; Schumacher, Ton N M.

Ann N Y Acad Sci ; 1217: 139-53, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21251009

19.

Mapping the life histories of T cells.

Schumacher, Ton N M; Gerlach, Carmen; van Heijst, Jeroen W J.

Nat Rev Immunol ; 10(9): 621-31, 2010 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-20689559

20.

One naive T cell, multiple fates in CD8+ T cell differentiation.

Gerlach, Carmen; van Heijst, Jeroen W J; Swart, Erwin; Sie, Daoud; Armstrong, Nicola; Kerkhoven, Ron M; Zehn, Dietmar; Bevan, Michael J; Schepers, Koen; Schumacher, Ton N M.

J Exp Med ; 207(6): 1235-46, 2010 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-20479114

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