Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Gateway Arch to the RNA Exosome.

Losh, Jillian S; van Hoof, Ambro.

Cell ; 162(5): 940-1, 2015 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-26317461

2.

Fungi of the order Mucorales express a "sealing-only" tRNA ligase.

Ahammed, Khondakar Sayef; van Hoof, Ambro.

RNA ; 30(4): 354-366, 2024 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-38307611

3.

Coordination between aminoacylation and editing to protect against proteotoxicity.

Zhang, Hong; Murphy, Parker; Yu, Jason; Lee, Sukyeong; Tsai, Francis T F; van Hoof, Ambro; Ling, Jiqiang.

Nucleic Acids Res ; 51(19): 10606-10618, 2023 10 27.

Artigo em Inglês | MEDLINE | ID: mdl-37742077

4.

Conserved Residues at the Mtr4 C-Terminus Coordinate Helicase Activity and Exosome Interactions.

Yim, Matthew K; Stuart, Catherine J; Pond, Markell I; van Hoof, Ambro; Johnson, Sean J.

Biochemistry ; 63(1): 159-170, 2024 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-38085597

5.

New insights into RNA processing by the eukaryotic tRNA splicing endonuclease.

Hayne, Cassandra K; Sekulovski, Samoil; Hurtig, Jennifer E; Stanley, Robin E; Trowitzsch, Simon; van Hoof, Ambro.

J Biol Chem ; 299(9): 105138, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37544645

6.

Inactivation of the ribosome assembly factor RimP causes streptomycin resistance and impairs motility in Salmonella.

Lyu, Zhihui; Ling, Yunyi; van Hoof, Ambro; Ling, Jiqiang.

Antimicrob Agents Chemother ; : e0000224, 2024 Apr 17.

Artigo em Inglês | MEDLINE | ID: mdl-38629858

7.

Yeast Dxo1 is required for 25S rRNA maturation and acts as a transcriptome-wide distributive exonuclease.

Hurtig, Jennifer E; van Hoof, Ambro.

RNA ; 28(5): 657-667, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35140172

8.

Comparative parallel analysis of RNA ends identifies mRNA substrates of a tRNA splicing endonuclease-initiated mRNA decay pathway.

Hurtig, Jennifer E; Steiger, Michelle A; Nagarajan, Vinay K; Li, Tao; Chao, Ti-Chun; Tsai, Kuang-Lei; van Hoof, Ambro.

Proc Natl Acad Sci U S A ; 118(10)2021 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-33649230

9.

A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex.

Sterrett, Maria C; Enyenihi, Liz; Leung, Sara W; Hess, Laurie; Strassler, Sarah E; Farchi, Daniela; Lee, Richard S; Withers, Elise S; Kremsky, Isaac; Baker, Richard E; Basrai, Munira A; van Hoof, Ambro; Fasken, Milo B; Corbett, Anita H.

RNA ; 27(9): 1046-1067, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34162742

10.

Pontocerebellar hypoplasia associated with p.Arg183Trp homozygous variant in EXOSC1 gene: A case report.

Damseh, Nadirah S; Obeidat, Ali N; Ahammed, Khondakar Sayef; Al-Ashhab, Motee; Awad, Motee Abu; van Hoof, Ambro.

Am J Med Genet A ; 191(7): 1923-1928, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37024942

11.

Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness.

Slavotinek, Anne; Misceo, Doriana; Htun, Stephanie; Mathisen, Linda; Frengen, Eirik; Foreman, Michelle; Hurtig, Jennifer E; Enyenihi, Liz; Sterrett, Maria C; Leung, Sara W; Schneidman-Duhovny, Dina; Estrada-Veras, Juvianee; Duncan, Jacque L; Haaxma, Charlotte A; Kamsteeg, Erik-Jan; Xia, Vivian; Beleford, Daniah; Si, Yue; Douglas, Ganka; Treidene, Hans Einar; van Hoof, Ambro; Fasken, Milo B; Corbett, Anita H.

Hum Mol Genet ; 29(13): 2218-2239, 2020 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-32504085

12.

Origin, conservation, and loss of alternative splicing events that diversify the proteome in Saccharomycotina budding yeasts.

Hurtig, Jennifer E; Kim, Minseon; Orlando-Coronel, Luisa J; Ewan, Jellisa; Foreman, Michelle; Notice, Lee-Ann; Steiger, Michelle A; van Hoof, Ambro.

RNA ; 26(10): 1464-1480, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32631843

13.

Heme peroxidase HPX-2 protects Caenorhabditis elegans from pathogens.

Liu, Yi; Kaval, Karan Gautam; van Hoof, Ambro; Garsin, Danielle A.

PLoS Genet ; 15(1): e1007944, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30695063

14.

Conservation of mRNA quality control factor Ski7 and its diversification through changes in alternative splicing and gene duplication.

Marshall, Alexandra N; Han, Jaeil; Kim, Minseon; van Hoof, Ambro.

Proc Natl Acad Sci U S A ; 115(29): E6808-E6816, 2018 07 17.

Artigo em Inglês | MEDLINE | ID: mdl-29967155

15.

The Paralogous Transcription Factors Stp1 and Stp2 of Candida albicans Have Distinct Functions in Nutrient Acquisition and Host Interaction.

Miramón, Pedro; Pountain, Andrew W; van Hoof, Ambro; Lorenz, Michael C.

Infect Immun ; 88(5)2020 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-32094252

16.

Interaction between the RNA-dependent ATPase and poly(A) polymerase subunits of the TRAMP complex is mediated by short peptides and important for snoRNA processing.

Losh, Jillian S; King, Alejandra Klauer; Bakelar, Jeremy; Taylor, Lacy; Loomis, John; Rosenzweig, Jason A; Johnson, Sean J; van Hoof, Ambro.

Nucleic Acids Res ; 43(3): 1848-58, 2015 Feb 18.

Artigo em Inglês | MEDLINE | ID: mdl-25589546

17.

The RNA exosome affects iron response and sensitivity to oxidative stress.

Tsanova, Borislava; Spatrick, Phyllis; Jacobson, Allan; van Hoof, Ambro.

RNA ; 20(7): 1057-67, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24860016

18.

The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding.

Taylor, Lacy L; Jackson, Ryan N; Rexhepaj, Megi; King, Alejandra Klauer; Lott, Lindsey K; van Hoof, Ambro; Johnson, Sean J.

Nucleic Acids Res ; 42(22): 13861-72, 2014 Dec 16.

Artigo em Inglês | MEDLINE | ID: mdl-25414331

19.

Alternative splicing and subfunctionalization generates functional diversity in fungal proteomes.

Marshall, Alexandra N; Montealegre, Maria Camila; Jiménez-López, Claudia; Lorenz, Michael C; van Hoof, Ambro.

PLoS Genet ; 9(3): e1003376, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23516382

20.

A brief survey of mRNA surveillance.

van Hoof, Ambro; Wagner, Eric J.

Trends Biochem Sci ; 36(11): 585-92, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21903397

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