Detalhe da pesquisa
1.
The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability.
Liver Int
; 44(3): 760-775, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38217387
2.
Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.
Breast Cancer Res
; 25(1): 51, 2023 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37147730
3.
Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia.
Breast Cancer Res Treat
; 198(3): 583-596, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826702
4.
An Adverse Outcome Pathway Network for Chemically Induced Oxidative Stress Leading to (Non)genotoxic Carcinogenesis.
Chem Res Toxicol
; 36(6): 805-817, 2023 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156502
5.
Model-based translation of DNA damage signaling dynamics across cell types.
PLoS Comput Biol
; 18(7): e1010264, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802572
6.
High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitors.
Cell Biol Toxicol
; 39(2): 415-433, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35505273
7.
Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells.
Cell Biol Toxicol
; 39(6): 3031-3059, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353587
8.
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
Arch Toxicol
; 97(2): 523-545, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36576512
9.
Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters.
Mutagenesis
; 37(2): 130-142, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34448005
10.
Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes.
Cell Biol Toxicol
; 38(5): 847-864, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34021431
11.
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
Arch Toxicol
; 96(1): 259-285, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34642769
12.
In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.
Small
; 17(15): e2006055, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33448117
13.
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
Arch Toxicol
; 95(12): 3745-3775, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34626214
14.
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages.
Arch Toxicol
; 95(10): 3285-3302, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480604
15.
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors.
Arch Toxicol
; 95(2): 591-615, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512557
16.
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Arch Toxicol
; 95(2): 573-589, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106934
17.
The hepatotoxic fluoroquinolone trovafloxacin disturbs TNF- and LPS-induced p65 nuclear translocation in vivo and in vitro.
Toxicol Appl Pharmacol
; 391: 114915, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32035082
18.
Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action.
Arch Toxicol
; 94(5): 1655-1671, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32189037
19.
Correction to: Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
Arch Toxicol
; 94(8): 2731-2732, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32720191
20.
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
Arch Toxicol
; 94(8): 2707-2729, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32607615