Convolutions of dentigerous cyst: An institutional experience.

OBJECTIVE: Statement of the Problem: Benign appearing dentigerous cyst (DC), also the most common developmental odontogenic cyst, shows various complications due to its pluripotent cell lining. The spectrum of diseases produced by conversion of its pluripotent cell varies from unicystic ameloblastoma, intraosseous epidermoid and central mucoepidermoid carcinoma. So, the need of the hour is to be acquainted with the etiopathogenesis of DC at molecular level and an attempt should be made to minimize its rate of tumor conversion. PURPOSE: To analyze the potential complications, their demographic profile, disease characteristics which can arise from the dentigerous cyst, and to be geared up for such situations in future. MATERIALS AND METHOD: Retrospective analysis was conducted and data was collected from the requisition forms during the time frame 2011- 2016 in the Department at Government Dental College, Haryana. Histopathologically diagnosed cases of dentigerous cyst were reviewed by three different observers and recorded, out of which DCs that showed potential complications were reviewed in detail. RESULTS: Six cases of DC out of 26 showed transformation into central mucoepidermoid carcinoma, adenomatoid odontogenic tumor (two) and ameloblastoma (three) respectively. CONCLUSION: The present research highlights the probable complications of DC encountered in our institute and conscientious vigilance should be exercised while histopathological examination of biopsied specimens. This study further unravels the enigma behind the emergence of neoplasms arising from DC.

Changing Trends of Odontogenic Cysts and Tumors in Kenya: A 20-Year Retrospective Analysis.

OBJECTIVES: This study endeavors to bridge the long-term diagnostic and management gap through a comprehensive audit of odontogenic cysts and tumors in Kenya, offering crucial insights for both clinicians and policymakers. METHODS: Patient records (2001-2020) with odontogenic cysts and tumors were retrospectively abstracted from two major referral hospitals in Nairobi, Kenya, covering demographics, lesion location, and histological diagnosis. IBM SPSS Statistics for Windows, Version 29.0 (Released 2023; IBM Corp., Armonk, New York, United States) was used for data analysis which included all descriptive statistics, student t-tests, chi-square tests, and one-way ANOVA. RESULTS: A total of 1889 cases were analyzed. Males exhibited a significantly higher prevalence of cysts and tumors (p < 0.001). Odontogenic tumors dominated in the age group of 21-30 years, while cysts were prevalent in the age group of 11-20 years. Ameloblastoma was the most prevalent tumor (n=853; 84.1%) while dentigerous cysts were the most common cysts (n = 468; 53.5%), both demonstrating a male predilection. The mean age at presentation and site predilection of each tumor and cyst were also detailed. CONCLUSION: This study provides crucial insights into odontogenic cysts and tumors in Kenya emphasizing geographic variations, age-specific patterns, and gender disparities for more effective diagnostic and management strategies, especially in resource-limited settings, to improve outcomes and reduce associated morbidity and mortality.

Cholesterol Granuloma From a Developmental Odontogenic Cyst: A Report of a Rare Case and a Literature Review.

Dentigerous cysts are the second most common developmental odontogenic cysts that develop around the crown of unerrupted teeth with the maxillary canine region being one of the common sites of occurrence. The cystic lining of this lesion has been shown to develop into ameloblastoma, Muco epidermoid carcinoma, and squamous cell carcinomas. However, the development of cholesterol granuloma (CG) in the cystic lining of a dentigerous cyst is extremely rare. CG is a histological observation distinguished by the presence of a conglomeration of connective tissue and granulation tissue. The condition is predominantly seen in the field of otolaryngology, with very few cases reported in the maxillofacial region, most of which are associated with the maxillary sinus. This article presents the findings of a CG in a 39-year-old male patient that developed within the dentigerous cyst and discusses the possible etiopathogenesis, surgical management, and histological presentation.

Dentigerous Cyst in a Pediatric Patient: A Case Report.

One of the most prevalent types of odontogenic cysts is a dentigerous cyst, which is usually connected to the crown of an immature tooth. We report the case of an 11-year-old boy, who had a swelling over his left cheek, which was determined to be a dentigerous cyst by radiological imaging and clinical examination. Over the course of two months, the peanut-sized mass grew to 3x2 cm. A massive, well-defined cystic lesion connected to an unerupted premolar tooth was found on a CT scan of the left maxillary alveolar arch and sinus floor. Under general anesthesia, the patient had a Caldwell-Luc surgery to remove the cyst. In order to avoid difficulties related to cyst formation, which can invade surrounding tissues and even result in cancer if left untreated, early detection using radiological imaging is essential. Complete excision of the cyst is the treatment, particularly for big lesions, in order to limit morbidity and lower the likelihood of aggressive behavior. This case emphasizes the necessity of thorough examination and surgical intervention when necessary, underscoring the significance of early identification and adequate therapy to minimize potential problems related to dentigerous cysts. In cases of dentigerous cysts, early intervention, and appropriate surgical procedures are critical to reducing morbidity and improving patient outcomes.

A Case of Primary Intraosseous Squamous Cell Carcinoma Arising in Dentigerous Cyst of Mandible.

Primary intraosseous squamous cell carcinoma (PISCC) arising from dentigerous cysts (DCs) is rare. Herein, we present a rare case of a 35 year-old Japanese man with PISCC arising from a DC. Clinicians should be aware of the potential for malignant changes to SCC in asymptomatic DCs and should conduct follow-up. Moreover, histological examination of the entire specimen should be performed even if the lesion is suspected to be benign.

Marsupialization of a Large Dentigerous Cyst in the Mandible: A Case Report.

Dentigerous cysts (DCs) are one of the most common cysts in the oral and maxillofacial region, and they are often discovered by chance in young people. The methods of treatment differ according to the size they reach, but the prognosis and results of the treatment are generally good. DCs are often associated with impacted teeth, especially mandibular third molars and maxillary canines, and they are usually discovered when they reach large sizes or get infected after they have caused great absorption and destruction of the surrounding cortical bone and displacement in adjacent teeth. This case report expresses the importance of conservative treatment of large oral cysts (by marsupialization) in the preservation of jaw bones, in a young female child of 12 years, with a DC associated with an impacted second permanent lower molar. This cyst occupied nearly half of the mandible with the danger of causing more harm to the jaw. In brief, marsupialization is a very effective method of treatment for DCs, especially those that reach very large volumes.