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1.
Int J Mol Sci ; 25(4)2024 Feb 13.
Artigo em Inglês | MEDLINE | ID: mdl-38396899

RESUMO

The Second International StemNet (Federation of Stem Cell Research Associations) meeting took place on 18-20 October 2023 in Brescia (Italy), with the support of the University of Brescia and the Zooprophylactic Institute of Lombardy and Emilia Romagna. The program of the meeting was articulated in nine sections: (1) Biomedical Communication in Italy: Critical Aspects; (2) StemNet Next Generation Session; (3) Cell-Free Therapies; (4) Tips and Tricks of Research Valorisation; (5) Stem Cells and Cancer; (6) Stem Cells in Veterinary Applications; (7) Stem Cells in Clinical Applications; (8) Organoids and 3D Systems; (9) induced pluripotent stem cells (iPCS) and Gene Therapy. National and International speakers presented their scientific works, inspiring debates and discussions among the attendees. The participation in the meeting was high, especially because of the young researchers who animated all the sessions and the rich poster session.


Assuntos
Células-Tronco Pluripotentes Induzidas , Neoplasias , Humanos , Neoplasias/terapia , Itália , Terapia Genética , Terapia Baseada em Transplante de Células e Tecidos
2.
Int J Mol Sci ; 24(10)2023 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-37240248

RESUMO

The 2022 Italian Mesenchymal Stem Cell Group (Gruppo Italiano Staminali Mesenchimali, GISM) Annual Meeting took place on 20-21 October 2022 in Turin (Italy), with the support of the University of Turin and the City of Health and Science of Turin. The novelty of this year's meeting was its articulation, reflecting the new structure of GISM based on six sections: (1) Bringing advanced therapies to the clinic: trends and strategies, (2) GISM Next Generation, (3) New technologies for 3D culture systems, (4) Therapeutic applications of MSC-EVs in veterinary and human medicine, (5) Advancing MSC therapies in veterinary medicine: present challenges and future perspectives, (6) MSCs: a double-edged sword: friend or foe in oncology. National and international speakers presented their scientific works with the aim of promoting an interactive discussion and training for all attendees. The atmosphere was interactive, where ideas and questions between younger researchers and senior mentors were shared in all moments of the congress.


Assuntos
Oncologia , Células-Tronco Mesenquimais , Humanos , Itália
3.
Int J Mol Sci ; 23(4)2022 Feb 11.
Artigo em Inglês | MEDLINE | ID: mdl-35216127

RESUMO

The annual meeting "Signal Transduction-Receptors, Mediators and Genes" of the Signal Transduction Society (STS) is an interdisciplinary conference which is open to all scientists sharing a common interest in the elucidation of the signaling pathways mediating physiological or pathological processes in the health and disease of humans, animals, plants, fungi, prokaryotes, and protists. The 24th meeting on signal transduction was held from 15 to 17 November 2021 in Weimar, Germany. As usual, keynote presentations by invited scientists introduced the respective workshops, and were followed by speakers chosen from the submitted abstracts. A special workshop focused on "Target Identification and Interaction". Ample time was reserved for the discussion of the presented data during the workshops. Unfortunately, due to restrictions owing to the SARS-CoV-2 pandemic, the poster sessions-and thus intensive scientific discussions at the posters-were not possible. In this report, we provide a concise summary of the various workshops and further aspects of the scientific program.


Assuntos
Transdução de Sinais/fisiologia , Pesquisa Biomédica , Alemanha , Sociedades Científicas
4.
Am J Kidney Dis ; 76(6): 842-850, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32768631

RESUMO

Occasional bursts of discovery and innovation have appeared during the otherwise stagnant past several decades of drug development in nephrology. Among other recent drug discoveries, the unexpected kidney benefits observed with sodium/glucose cotransporter 2 inhibitors may herald a renaissance of drug development in kidney disease. This recent progress highlights the need to further promote and stimulate research and development of promising therapies that may ameliorate the morbidity and mortality associated with kidney disease. To help identify and address barriers to drug development in nephrology, the Duke Clinical Research Institute convened a conference in April 2019 that included stakeholders from academia, industry, government agencies, and patient advocacy. From these discussions, several opportunities were identified to improve every stage of drug development for kidney disease from early discovery to implementation into practice. Key topics reviewed in this article are the utility of interconnected data and site research networks, surrogate end points, pragmatic and adaptive trial designs, the promising uses of real-world data, and methods to improve the generalizability of trial results and uptake of approved drugs for kidney-related diseases.


Assuntos
Desenvolvimento de Medicamentos/métodos , Nefropatias/tratamento farmacológico , Projetos de Pesquisa , Aprovação de Drogas , Humanos
5.
Int J Mol Sci ; 21(2)2020 Jan 17.
Artigo em Inglês | MEDLINE | ID: mdl-31963503

RESUMO

The sixth meeting of the International Society for Zinc Biology (ISZB-2019) was held on September 9-13, 2019 in Kyoto, Japan. The meeting attracted 215 participants, had four plenary speakers, ten scientific symposia, two oral sessions, and one poster discussion session. In this chapter, we describe the outcomes and events of this very successful meeting.


Assuntos
Congressos como Assunto , Hipersensibilidade a Drogas/fisiopatologia , Zinco/fisiologia , Humanos , Internacionalidade , Japão , Sociedades Médicas , Zinco/administração & dosagem
6.
Int J Mol Sci ; 21(8)2020 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-32326408

RESUMO

The annual meeting "Signal Transduction-Receptors, Mediators and Genes" of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating the signalling pathways underlying the physiological or pathological processes in health and disease of humans, animals, plants, fungi, prokaryotes and protists. The 23rd meeting on signal transduction was held from 4-6 November 2019 in Weimar, Germany, and focused on "Trends in Cancer and Infection". As usual, keynote presentations by invited scientists introduced the respective workshops and were followed by speakers chosen from the submitted abstracts. Ample time had been reserved for discussion of the presented data during the workshops. In this report, we provide a concise summary of the various workshops and further aspects of the scientific program.


Assuntos
Doenças Transmissíveis/imunologia , Neoplasias/imunologia , Neoplasias/metabolismo , Transdução de Sinais , Animais , Doenças Transmissíveis/metabolismo , Doenças Transmissíveis/microbiologia , Doenças Transmissíveis/parasitologia , Alemanha , Humanos , Neoplasias/genética , Transdução de Sinais/imunologia
7.
Int J Mol Sci ; 20(1)2019 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-30626122

RESUMO

The annual meeting "Signal Transduction-Receptors, Mediators, and Genes" of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating signaling pathways in physiological or pathological processes in humans, animals, plants, fungi, prokaryotes, and protists. On the occasion of the 20th anniversary of the STS, the 22nd joint meeting took place in Weimar from 5⁻7 November 2018. With the focus topic "Signaling: From Past to Future" the evolution of the multifaceted research concerning signal transduction since foundation of the society was highlighted. Invited keynote speakers introduced the respective workshop topics and were followed by numerous speakers selected from the submitted abstracts. All presentations were lively discussed during the workshops. Here, we provide a concise summary of the various workshops and further aspects of the scientific program.


Assuntos
Transdução de Sinais , Animais , Morte Celular , Modelos Animais de Doenças , Humanos , Camundongos , Neoplasias/metabolismo , Neoplasias/patologia , Neurônios/metabolismo , Proteína Supressora de Tumor p53/metabolismo
8.
Int J Mol Sci ; 19(2)2018 Feb 12.
Artigo em Inglês | MEDLINE | ID: mdl-29439515

RESUMO

The annual "Joint Meeting Signal Transduction-Receptors, Mediators and Genes" of the Signal Transduction Society (STS) aims to be an interdisciplinary forum for researchers who share a common interest in deciphering signal transduction pathways in normal or transformed cells, in health and disease, in humans and animal models, or in plants or bacteria. The special focus of the 21st annual Joint Meeting, which took place from 8-10 November 2017 in Weimar, was the topic "Metabolism in Health and Disease" and covered multiple aspects of this highly exciting and fast developing research field. Invited keynote speakers introduced the impact of metabolism on tumor immunology, immune cell signaling, and posttranslational modifications in three specific workshops to the audience. Various other aspects of signal transduction were intensively discussed in five additional workshops. Here, we give an overview of the various workshops and further aspects of the scientific program.


Assuntos
Transdução de Sinais , Sociedades Científicas , Distinções e Prêmios , Alemanha , Metabolismo
9.
Int J Mol Sci ; 18(12)2017 11 24.
Artigo em Inglês | MEDLINE | ID: mdl-29186798

RESUMO

From 18 to 22 June 2017, the fifth biennial meeting of the International Society for Zinc Biology was held in conjunction with the final dissemination meeting of the Network for the Biology of Zinc (Zinc-Net) at the University of Central Lancashire, Cyprus campus. The meeting attracted over 160 participants, had 17 scientific symposia, 4 plenary speakers and 2 poster discussion sessions. In this report, we give an overview of the key themes of the meeting and some of the highlights from the scientific programme.


Assuntos
Congressos como Assunto , Zinco/metabolismo , Animais , Chipre , Humanos , Zinco/deficiência
10.
Int J Mol Sci ; 17(9)2016 Sep 08.
Artigo em Inglês | MEDLINE | ID: mdl-27618023

RESUMO

Despite the identification of circulating tumor cells (CTCs) and cell-free DNA (cfDNA) as potential blood-based biomarkers capable of providing prognostic and predictive information in cancer, they have not been incorporated into routine clinical practice. This resistance is due in part to technological limitations hampering CTC and cfDNA analysis, as well as a limited understanding of precisely how to interpret emergent biomarkers across various disease stages and tumor types. In recognition of these challenges, a group of researchers and clinicians focused on blood-based biomarker development met at the Canadian Cancer Trials Group (CCTG) Spring Meeting in Toronto, Canada on 29 April 2016 for a workshop discussing novel CTC/cfDNA technologies, interpretation of data obtained from CTCs versus cfDNA, challenges regarding disease evolution and heterogeneity, and logistical considerations for incorporation of CTCs/cfDNA into clinical trials, and ultimately into routine clinical use. The objectives of this workshop included discussion of the current barriers to clinical implementation and recent progress made in the field, as well as fueling meaningful collaborations and partnerships between researchers and clinicians. We anticipate that the considerations highlighted at this workshop will lead to advances in both basic and translational research and will ultimately impact patient management strategies and patient outcomes.


Assuntos
Biomarcadores Tumorais/sangue , Ensaios Clínicos como Assunto , DNA de Neoplasias/sangue , DNA/sangue , Células Neoplásicas Circulantes/patologia , Humanos , Células Neoplásicas Circulantes/metabolismo
11.
J Carcinog ; 14: 4, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26085817

RESUMO

The search for the most effective therapy with minimum side effects has always been the goal of oncologists and efforts to develop such therapies through understanding disease mechanisms has been the focus of many basic scientists in cancer research, leading to a common interest of convergence. The 5(th) International Conference organized by the Carcinogenesis Foundation, USA and Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, India, was held between February 11(th) and 13(th) 2015, at ACTREC. During these proceedings, the scientific community engaged in oncology research discussed novel ideas emerging from the laboratory and their translation into improved clinical outcomes. However, the lack of major success in the genesis of novel cancer therapeutics that is safe and provides long-term relief to patients is a challenge that needs to be overcome. The focus of this meeting was to highlight these challenges and to encourage collaborations between scientists and clinicians and clearly a message through exemplary scientific contribution was conveyed to all the dedicated scientists and clinician that even if two decades of tireless work on a single idea does not generate a reliable and safe therapy, the combat to rein cancer must not cease. In this report we have communicated some of the outstanding work done in the areas of cancer therapeutics, biomarkers and prevention and described the salient observations associated with cancer stem cells in disease progression and some of the pathways implicated in tumor progression.

12.
FEBS Open Bio ; 14 Suppl 1: 3-11, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38735909

RESUMO

The 2nd International FEBS-IUBMB-ENABLE Molecular Biosciences PhD and Postdoc Conference was held from 23rd to 25th November 2023 in Cologne, Germany. Over 240 participants from 31 different countries came together at the University of Cologne to follow the two-day scientific symposium and the career day. This year's topic was "The emerging challenge - environmental impacts on human health". In four different sessions, eight renowned keynote speakers presented their current research. By offering flash and short talks, 39 participants were able to present their work in front of a big audience. Scientific exchange and networking were encouraged during the two poster sessions, during breaks, and the conference dinner. On the Career Day, a career fair was held and participants could attend workshops as well as career chats to improve their job prospects. The success of the series will be continued during the next conference edition: "Artificial Intelligence - Reshaping biomedical and healthcare research", which will take place 4th to 6th December 2024 in Singapore.


Assuntos
Meio Ambiente , Humanos , Biologia Molecular
13.
Virology ; 594: 110049, 2024 06.
Artigo em Inglês | MEDLINE | ID: mdl-38527382

RESUMO

The Second International Conference of the World Society for Virology (WSV), hosted by Riga Stradins University, was held in Riga, Latvia, on June 15-17th, 2023. It prominently highlighted the recent advancements in different disciplines of virology. The conference had fourteen keynote speakers covering diverse topics, including emerging virus pseudotypes, Zika virus vaccine development, herpesvirus capsid mobility, parvovirus invasion strategies, influenza in animals and birds, West Nile virus and Marburg virus ecology, as well as the latest update in animal vaccines. Discussions further explored SARS-CoV-2 RNA replicons as vaccine candidates, SARS-CoV-2 in humans and animals, and the significance of plant viruses in the 'One Health' paradigm. The presence of the presidents from three virology societies, namely the American, Indian, and Korean Societies for Virology, highlighted the event's significance. Additionally, past president of the American Society for Virology (ASV), formally declared the partnership between ASV and WSV during the conference.


Assuntos
Vacinas contra Influenza , Saúde Única , Vírus , Infecção por Zika virus , Zika virus , Animais , Humanos , RNA Viral , Virologia
14.
Ann N Y Acad Sci ; 1535(1): 31-41, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38593220

RESUMO

In 2023, the Keystone Symposia held the first international scientific conference convening research leaders investigating the pathology of post-acute sequelae of COVID-19 (PASC) or Long COVID, a growing and urgent public health priority. In this report, we present insights from the talks and workshops presented during this meeting and highlight key themes regarding what researchers have discovered regarding the underlying biology of PASC and directions toward future treatment. Several themes have emerged in the biology, with inflammation and other immune alterations being the most common focus, potentially related to viral persistence, latent virus reactivation, and/or tissue damage and dysfunction, especially of the endothelium, nervous system, and mitochondria. In order to develop safe and effective treatments for people with PASC, critical next steps should focus on the replication of major findings regarding potential mechanisms, disentangling pathogenic mechanisms from downstream effects, development of cellular and animal models, mechanism-focused randomized, placebo-controlled trials, and closer collaboration between people with lived experience, scientists, and other stakeholders. Ultimately, by learning from other post-infectious syndromes, the knowledge gained may help not only those with PASC/Long COVID, but also those with other post-infectious syndromes.


Assuntos
COVID-19 , Síndrome de COVID-19 Pós-Aguda , SARS-CoV-2 , Humanos , COVID-19/terapia , COVID-19/complicações , COVID-19/virologia , SARS-CoV-2/patogenicidade , Tratamento Farmacológico da COVID-19
15.
J Psychosom Res ; : 111461, 2023 Aug 18.
Artigo em Inglês | MEDLINE | ID: mdl-37633798

RESUMO

Several hundred participants from all over the world, 36 sessions and workshops, 10 experts in the field of psychosomatics, and Nobel Prize Winner, Olga Tokarczuk, made the 10th European Association of Psychosomatic Medicine scientific conference held in Wroclaw, Poland in June 2023, a huge success.

16.
FEBS Open Bio ; 13 Suppl 1: 1-8, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-37325949

RESUMO

The FEBS-IUBMB-ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference was held in Seville, Spain, from the 16-18th of November 2022. Nearly 300 participants from all over the globe were welcomed by the host institution, the Institute of Biomedicine of Seville (IBiS). Following the theme "The perfect tandem: How technology expands the frontiers of biomedicine", the Scientific Symposium of the conference hosted eight world-renowned keynote speakers who presented their work in one of the four sessions: Innovation, Basic Research, Translational and Clinical Research, and Computational Biology and Artificial Intelligence. Participants had the chance to present their research to their peers: more than 200 posters were presented during the dedicated poster sessions and 19 selected PhD students and postdocs presented their work as short talks. The Career Day featured a wide range of workshops fully devoted to trainees' professional development, as well as a job fair and career chats with professionals to discuss future perspectives. Besides, several outreach activities were organised before and during the conference to engage with the general public and bring science closer to society. The success of this conference will be followed by the next FEBS-IUBMB-ENABLE conferences in Cologne, Germany, in 2023 and Singapore in 2024.


Assuntos
Inteligência Artificial , Biologia Computacional , Humanos , Pesquisadores
17.
Viruses ; 15(10)2023 10 20.
Artigo em Inglês | MEDLINE | ID: mdl-37896906

RESUMO

The XVIII International Parvovirus Workshop took place in Rimini, Italy, from 14 to 17 June 2022 as an on-site event, continuing the series of meetings started in 1985 and continuously held every two years. The communications dealt with all aspects of research in the field, from evolution and structure to receptors, from replication to trafficking, from virus-host interactions to clinical and veterinarian virology, including translational issues related to viral vectors, gene therapy and oncolytic parvoviruses. The oral communications were complemented by a poster exhibition available for view and discussion during the whole meeting. The XVIII International Parvovirus Workshop was dedicated to the memory of our dearest colleague Mavis Agbandje-McKenna (1963-2021).


Assuntos
Infecções por Parvoviridae , Parvovirus , Humanos , Parvovirus/genética , Vetores Genéticos , Itália
18.
Ecancermedicalscience ; 17: 1517, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37113728

RESUMO

The Choosing Wisely campaign was formally launched in 2012 and a decade later, the inaugural Choosing Wisely Africa conference was held in Dakar, Senegal on 16 December 2022 supported by ecancer. Academic partners included Ministere de la Sante et de I'Action Sociale, Senegalese Association of Palliative Care, Federation Internationale des Soins Palliatifs, Universite Cheikh Anta diop de Dakar, Societe Senegalaise de Cancerologie and King's College London. There were around 70 delegates attending in person mostly from Senegal and a further 30 joining virtually. Ten speakers gave insight into Choosing Wisely from an African perspective and Dr's Fabio Moraes and Frederic Ivan Ting shared the Choosing Wisely experience from Brazil and the Philippines, respectively. This report therefore shares the highlights of the first Choosing Wisely Africa conference guided by topics discussed.

19.
J Pediatr Surg ; 57(2): 165-166, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34839948

RESUMO

The LXVII British Association of Paediatric Surgeons (BAPS) was held virtually in July 2021. The programme included scientific presentations, invited lectures, and societal awards including the Denis Browne Gold Medal to Mr David Thomas. The BAPS Congress issue comprises 20 submitted papers based on podium presentations and 4 papers based on the invited lectures. LEVEL OF EVIDENCE: : IV.


Assuntos
Sociedades Médicas , Cirurgiões , Criança , Humanos
20.
Biochem Mol Biol Educ ; 50(5): 440-445, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35815748

RESUMO

Biochemistry is a data-heavy discipline, yet teaching students to work with large datasets is absent from many undergraduate Biochemistry programs. Ensuring that future generations of students arevbv confident in tackling problems using big data first requires that educators become comfortable teaching big data skills. The activity described herein introduces educators to working with big data and a framework for generating sequence similarity networks using JupyterLab and Python. This article reports a session from the virtual international 2021 IUBMB/ASBMB workshop, "Teaching Science with Big Data."


Assuntos
Big Data , Bioquímica , Bioquímica/educação , Evolução Biológica , Humanos , Estudantes , Ensino
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