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Bioanalysis ; 12(20): 1449-1458, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32975432

RESUMO

Aim: Current blood monitoring methods require sample collection and testing at a central lab, which can take days. Point of care (POC) devices with quick turnaround time can provide an alternative with faster results, allowing for real-time data leading to better treatment decisions for patients. Results/Methodology: An assay to measure monoclonal antibody therapeutic-A was developed on two POC devices. Data generated using 75 serum samples (65 clinical & ten spiked samples) show correlative results to the data generated using Gyrolab technology. Conclusion: This case study uses a monoclonal antibody therapeutic-A concentration assay as an example to demonstrate the potential of POC technologies as a viable alternative to central lab testing with quick results allowing for real-time decision-making.


Assuntos
Anticorpos Monoclonais/imunologia , Sistemas Automatizados de Assistência Junto ao Leito/normas , Humanos
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