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1.
Epilepsy Behav ; 152: 109693, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38368722

RESUMO

INTRODUCTION: Post-traumatic seizures (PTS) are common among patients with depressed skull fractures (DSF). Understanding the burden of post traumatic seizures and the factors associated among adult patients with DSF is important to improve clinical care. OBJECTIVE: To determine the prevalence and factors associated with post-traumatic seizures among adult patients with DSF at Mulago National Referral hospital (MNRH). METHODS: A cross-sectional study was conducted among 333 study participants between March 2021 and February 2022. Socio-demographic, clinical laboratory factors and anti-seizure medications were collected using a study questionnaire. Data was analysed to determine the prevalence of PTS and factors associated with occurrence of PTS among patients with DSF. RESULTS: The mean age (±SD) of study participants was 31.2, (±10.5) years, with a male to female ratio of 10.4:1. Nearly half of the study participants had attained secondary level of education, while 31.6 % (105) were peasants (subsistence farmers). The overall prevalence of PTS among DSF study participants was 16.2 % (54participants). Late presentation of PTS was the highest at 9.0 % (30) followed by early PTS at 3.9 % [13] and immediate PTS at 3.3 % [11]. Moderate Glasgow coma score (GCS: 9-13), p < 0.015, severe traumatic brain injury (GCS: 3-8), p < 0.026 at the time of admission and midline brain shift (≥5mm), p < 0.009 were associated with PTS. Phenytoin (94.3 %) was the most commonly used ASM followed by phenobarbitone (1.4 %) and Valproate (1.1 %) among study participants. CONCLUSION: Patients with moderate and severe traumatic brain injury and midline brain shift were associated with post traumatic seizures. Early identification and intervention may reduce the burden of posttraumatic seizures in this category of patients.


Assuntos
Lesões Encefálicas Traumáticas , Epilepsia Pós-Traumática , Fratura do Crânio com Afundamento , Adulto , Humanos , Masculino , Feminino , Estudos Transversais , Fratura do Crânio com Afundamento/complicações , Fatores de Risco , Epilepsia Pós-Traumática/complicações , Lesões Encefálicas Traumáticas/complicações , Hospitais
2.
Childs Nerv Syst ; 40(6): 1833-1838, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38411706

RESUMO

PURPOSE: Depressed ("ping-pong") skull fractures can be treated by different means, including observation, non-surgical treatments, or surgical intervention. The authors describe their experience with vacuum-assisted elevation of ping-pong skull fractures and evaluate variables associated with surgical outcomes. METHODS: The authors present a retrospective review of all ping-pong skull fractures treated with vacuum-assisted elevation at the Children's Hospital of Orange County in 2021-2022. Variables included patient age, mechanism of injury, fracture depth, bone thickness at the fracture site, and degree of elevation. RESULTS: Seven patients underwent vacuum-assisted elevation of ping-pong fractures at the bedside without the use of anesthesia. Fractures caused by birth-related trauma were deeper than those caused by falls (p < 0.001). There was no significant difference between groups in bone thickness at the fracture site (2.10 mm vs 2.16 mm, n.s). Six of the seven patients experienced significant improvement in fracture site depression, with four displaying a complete fracture reduction and two displaying a significant reduction. The degree of fracture reduction was modestly related to the depth of fracture, with the two deepest fractures failing to achieve full reduction. Age appeared to be related to fracture reduction, with the lowest reduction observed in one of the oldest patients in this sample. No complications were observed in any patient other than temporary mild swelling at the suction site, and no re-treatment or surgery for the fractures was required. CONCLUSION: Vacuum-assisted elevation of ping-pong skull fractures is a safe and effective noninvasive treatment option for infants that can be used under certain circumstances. The procedure can be done safely at the bedside and is a relatively quick procedure. It avoids the need for open surgical intervention, anesthesia, or hospital admission, and can lead to excellent outcomes.


Assuntos
Fratura do Crânio com Afundamento , Humanos , Masculino , Feminino , Estudos Retrospectivos , Lactente , Pré-Escolar , Fratura do Crânio com Afundamento/cirurgia , Fratura do Crânio com Afundamento/diagnóstico por imagem , Criança , Vácuo , Resultado do Tratamento
3.
Childs Nerv Syst ; 40(4): 1213-1219, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38157046

RESUMO

PURPOSE: The management of depressed skull fractures in infants can be either conservative or surgical. This study aimed to examine the outcomes of management with a negative-pressure vacuum device on depressed skull fractures in newborns. METHODS: Twenty-eight patients (aged 1-6 days) with simple depressed skull fractures underwent skull elevation using negative-pressure vacuum devices. A protocol for nonsurgical management was adopted for infants with such fractures between 2010 and 2023. All patients were initially evaluated with neurological examination and complementary assessments-hematological and coagulation studies, transfontanel transcranial ultrasound, skull radiography, and computed tomography scanning with three-dimensional reconstruction-according to availability and clinical needs. Gentle (negative) extraction pressure was applied with one of several devices (according to institutional availability) for a maximum duration of 60 s; this was performed as soon as possible after diagnosis, preferably within 72 h. Follow-up data, available in the clinical records, were reported. RESULTS: All patients exhibited satisfactory elevation of the depressed bone without associated injuries, except one patient who presented with an associated cephalohematoma which prevented optimal device coupling to generate sufficient vacuum pressure for correction. Neither neurological deficits nor development of epilepsy was noted; normal neurological assessment and oral alimentation tolerance were confirmed within 24 h post procedure. CONCLUSIONS: According to our data, ping-pong skull fracture elevation using the vacuum method is a safe and satisfactory treatment in the neonatal period. Early treatment allows for quick resolution, and in our opinion is the strategy of choice for depressed skull fractures in newborns.


Assuntos
Fratura do Crânio com Afundamento , Fraturas Cranianas , Lactente , Humanos , Recém-Nascido , Vácuo , Crânio , Cabeça
4.
Acta Neurochir (Wien) ; 166(1): 47, 2024 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-38286923

RESUMO

CONTEXT: Penetrating craniocerebral injury associated with depressed skull fracture is an infrequent yet timely neurosurgical emergency. Such injury frequently occurs in the frontal region during traffic accident or stone throw in the civilian setting. As military neurosurgeons, we present our experience in the surgical debridement and reconstruction of this peculiar type of traumatic brain injury. METHODS: The patient lies supine, the head in neutral position heal by a Mayfield head clamp. The first step is the debridement of the frontal wound. Then, the depressed skull fracture is operated on using a tailored coronal approach through Merkel dissection plane, in order to keep a free pericranial flap. The bone flap is cut around the depressed skull fracture. Neuronavigation allows to locate the frontal sinus depending on whether it has been breached and thus requires cranialization. Brain and dura mater debridement and plasty are performed. Cranioplasty is performed using either native bone fragments fixed with bone plates or tailored titanium plate if they are too damaged. CONCLUSION: Performing wounded skin closure first and then a tailored coronal approach with free pericranial flap and a craniotomy encompassing the depressed skull fracture allows to treat frontal penetrating craniocerebral injury in an easy-to-reproduce manner.


Assuntos
Traumatismos Craniocerebrais , Retalhos de Tecido Biológico , Fratura do Crânio com Afundamento , Fraturas Cranianas , Ferimentos Penetrantes , Humanos , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fratura do Crânio com Afundamento/cirurgia , Crânio/cirurgia , Traumatismos Craniocerebrais/cirurgia , Craniotomia , Retalhos de Tecido Biológico/cirurgia , Fraturas Cranianas/complicações , Fraturas Cranianas/diagnóstico por imagem , Fraturas Cranianas/cirurgia
5.
Arch Gynecol Obstet ; 310(2): 673-684, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38871966

RESUMO

PURPOSE: To determine the obstetric factors affecting the development of depressed skull fracture in neonates. MATERIALS AND METHODS: This was a retrospectively cohort study on neonates born between July 2016 and August 2021. Neonates diagnosed with depressed skull fractures within one week of birth through X-ray and/or brain ultrasonography were included, and their mothers' obstetric characteristics were reviewed. RESULTS: There were 12 cases in 6791 live births. Five women were over 35 years old. All except two were nulliparous. Five cases were delivered from labor induction and others presented with spontaneous labor. Except for two cases, delivery occurred within an hour after full cervical dilatation. Two cases were assisted by vacuum. None displayed fetal distress signs such as low Apgar scores below 7, meconium staining, and umbilical cord pH under 7.2. All depressed fractures were found in the right parietal area. Three cases resulted in focal hyperechoic lesion in brain ultrasonography and two of them showed small hemorrhage-like lesion in magnetic resonance imaging. All depressed skull fractures improved within 6 months in followed X-rays or ultrasonography. CONCLUSIONS: There was no definitely associated obstetric condition for depressed skull fracture of neonates although nulliparous women were majority of the affected cases.


Assuntos
Fratura do Crânio com Afundamento , Humanos , Feminino , Recém-Nascido , Estudos Retrospectivos , Gravidez , Fratura do Crânio com Afundamento/diagnóstico por imagem , Adulto , Masculino , Parto Obstétrico/efeitos adversos , Traumatismos do Nascimento , Imageamento por Ressonância Magnética
6.
Pediatr Neurosurg ; 59(2-3): 94-101, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38461817

RESUMO

INTRODUCTION: Injury and subsequent thrombosis of the cerebral venous sinuses may be caused by closed head injuries secondary to a variety of different mechanisms. Skull fractures can lacerate or otherwise disrupt adjacent dural sinuses. The sequelae of such injuries may include thrombosis and either partial or total occlusion of the sinus, ultimately resulting in significant venous congestion. Sagittal sinus injury is associated with a more serious outcome due to the obligatory flow into the sinus, especially posterior to the coronal suture. In such cases, venous infarction may be a severe and life-threatening complication of head injury. CASE PRESENTATION: A 2-year-old female presented with a depressed skull fracture near the midline and a thrombus in the sagittal sinus. Anticoagulation, the standard treatment cerebral venous sinus thrombosis (CVST), was contraindicated due to intracranial hemorrhage, so immediate thrombectomy was performed with successful neurologic recovery at 9-month follow-up. To our knowledge, this case is the youngest patient documented to receive mechanical thrombectomy for superior sagittal sinus (SSS) thrombosis due to trauma. CONCLUSION: Closed head injuries in pediatric patients may be associated with CVST, with resulting venous drainage compromise and profound neurologic sequelae. Unlike adult patients with spontaneous CVST in which anticoagulation are the standard of care, pediatric patients experiencing traumatic CVST may have contraindications to anticoagulants. If the patient has a contraindication to anticoagulation such as intracranial bleeding, endovascular mechanical thrombectomy may be an effective intervention when performed by an experienced neurointerventionalist.


Assuntos
Seio Sagital Superior , Trombectomia , Humanos , Feminino , Pré-Escolar , Trombectomia/métodos , Seio Sagital Superior/cirurgia , Seio Sagital Superior/lesões , Trombose do Seio Sagital/cirurgia , Trombose do Seio Sagital/etiologia , Trombose dos Seios Intracranianos/cirurgia , Trombose dos Seios Intracranianos/diagnóstico por imagem , Fratura do Crânio com Afundamento/cirurgia , Fratura do Crânio com Afundamento/diagnóstico por imagem , Traumatismos Craniocerebrais/complicações , Traumatismos Craniocerebrais/cirurgia
7.
J Craniofac Surg ; 35(5): e457-e458, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38861318

RESUMO

This case study describes a fatal head injury in a 1-year-old child involved in a motor vehicle accident in Japan. The child, secured in a rear-facing child seat, was a passenger in a car driven by their mother when the offset car-to-car collision occurred. The car rotated counterclockwise before coming to a stop. Despite remaining secured in the child seat, the child suffered severe head trauma, leading to cardiac arrest. Autopsy computed tomography revealed a right open depressed fracture, left head contusion, traumatic subarachnoid hemorrhage, intraventricular hemorrhage, and pneumocephalus. The injury mechanism involved the child's head striking the right headrest, followed by a swing to the left, induced by the initial impact and subsequent rotational movement. This case highlights the importance of age-specific data in understanding pediatric injuries in motor vehicle accidents and improving child seat safety measures.


Assuntos
Acidentes de Trânsito , Sistemas de Proteção para Crianças , Humanos , Lactente , Evolução Fatal , Tomografia Computadorizada por Raios X , Masculino , Traumatismos Craniocerebrais , Parada Cardíaca/etiologia , Japão , Fratura do Crânio com Afundamento/diagnóstico por imagem , Hemorragia Subaracnoídea Traumática/diagnóstico por imagem , Hemorragia Subaracnoídea Traumática/etiologia
8.
Brain Inj ; 37(4): 352-355, 2023 03 21.
Artigo em Inglês | MEDLINE | ID: mdl-36703296

RESUMO

BACKGROUND: Depressed skull fractures are typically the consequence of high-impact injuries with inward buckling of the cranium. The majority of depressed skull fractures are managed conservatively in the absence of dural violation, sinus involvement, significant underlying hematoma, depressed fragment greater than 1 cm, wound infection, or gross wound contamination. Even in the presence of any of the aforementioned criteria, cranioplasty is typically considered an urgent procedure rather than a neurosurgical emergency. Rarely, a depressed fracture fragment can cause focal neurologic deficit(s) due to direct compression of the underlying eloquent cortex. CASE DESCRIPTION: A 40-year-old male presented to the emergency department after a mechanical fall with a left central facial nerve palsy, left hemiplegia, left hemianesthesia, and fixed right gaze deviation. The neurologic deficits observed were attributed to a combination of blunt force trauma to the head (i.e., coup-contrecoup injury) and the depressed fracture fragment compressing the underlying eloquent cortex. He underwent emergent cranioplasty with fragment elevation within 2 hours of the traumatic injury. At 6-month follow-up, he regained full neurologic function without any residual deficits. CONCLUSIONS: Our experience highlights a rare indication for emergent cranioplasty with an excellent functional outcome attributable to immediate fracture elevation and decompression of eloquent cortex.


Assuntos
Fratura do Crânio com Afundamento , Fraturas Cranianas , Ferimentos não Penetrantes , Masculino , Humanos , Adulto , Fratura do Crânio com Afundamento/complicações , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fraturas Cranianas/cirurgia , Hematoma
9.
Sud Med Ekspert ; 66(6): 45-48, 2023.
Artigo em Russo | MEDLINE | ID: mdl-38093429

RESUMO

THE OBJECTIVE: Is to develop a differential approach to determining the severity of harm caused to health in case of depressed skull injuries in infants, depending on their morphological features and the character of required treatment. The material included data from literature sources on the study of brain injuries in infants, clinical guidelines, describing the features of clinical picture and diagnosis of depressed skull fractures in infants and legal and regulatory framework of forensic medical evaluation of harm caused to health in injury. The following methods of research were used: logical-analytical, logical-synthetic (generalization), comparative, system-analytical (analysis of relations between facts) and radiological method. An algorithm for determining the severity of harm caused to health in depressed skull deformations by «ping-pong¼ type in an infant is proposed for discussion. The algorithm is based on the data from injury imaging techniques, including X-ray computed tomography, takes into account the clinical picture and the availability of indications for surgical treatment, and will allow to objectively assess the severity of harm caused to health in such cases.


Assuntos
Fraturas Ósseas , Fratura do Crânio com Afundamento , Fraturas Cranianas , Lactente , Humanos , Fratura do Crânio com Afundamento/etiologia , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fratura do Crânio com Afundamento/cirurgia , Crânio/diagnóstico por imagem , Cabeça , Radiografia
10.
Childs Nerv Syst ; 38(3): 669-672, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34097098

RESUMO

Depressed skull fractures from dog bites are common pediatric head injuries which are contaminated with native skin and canine oral flora. Outcomes can potentially be catastrophic. Thus, these injuries require proper initial management to prevent future complications. We present an 18-month-old female who was bitten by a Great Dane dog and resulted in a small left temporal depressed skull fracture with an underlying brain contusion. This was initially treated conservatively with antibiotics and bedside irrigation. Five weeks later, she developed a large multiloculated abscess with mass effect, which required surgical aspiration and wound debridement. After long-term antibiotics, she made a full neurologic recovery. Our case illustrates the importance of washing out a seemingly inconsequential depressed skull fracture from a dog bite to avoid development of a cerebral abscess.


Assuntos
Mordeduras e Picadas , Traumatismos Craniocerebrais , Fratura do Crânio com Afundamento , Fraturas Cranianas , Animais , Mordeduras e Picadas/complicações , Criança , Traumatismos Craniocerebrais/cirurgia , Desbridamento , Cães , Feminino , Humanos , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fraturas Cranianas/complicações , Fraturas Cranianas/diagnóstico por imagem
11.
Pediatr Neurosurg ; 57(2): 133-137, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34823255

RESUMO

INTRODUCTION: Although still considered quite harmless, nonpowder guns (NPG) may cause severe head injuries in children. We present the case of a depressed skull fracture with superior sagittal sinus involvement following NPG injury. Decision-making and surgical management are discussed, and the current literature concerning NPG-related pediatric head injuries is reviewed. CASE PRESENTATION: A 4-year-old boy hit by a compressed-air rifle came to our center. CT scan showed a depressed skull fracture of the occipital bone on the midline and intracranial penetration of some fragments of the pellet. CT angiography documented a compression of the superior sagittal sinus without thrombosis. Soon after hospital admission, the patient showed deterioration of the neurological status suggesting intracranial hypertension. Surgery was performed with fracture elevation, removal of metal fragments, and wound debridement. The patient had a full recovery without subsequent neurological deficits. DISCUSSION/CONCLUSION: Modern airguns may produce severe penetrating head injuries in children. Parents and physicians should be aware of the danger of NPG. Depressed skull fracture and dural venous sinus involvement can occur, and even a stable neurological condition may worsen. In such instances, a thorough preoperative assessment including vascular imaging is mandatory. The surgical risk is not negligible due to the possible injury of the sinus wall and subsequent intraoperative bleeding. This has to be weighted against potential complications of the penetrating injury, such as infection, sinus thrombosis, and intracranial hypertension. Our case suggests that prompt surgical treatment can be a safe and effective option.


Assuntos
Traumatismos Craniocerebrais , Hipertensão Intracraniana , Trombose dos Seios Intracranianos , Fratura do Crânio com Afundamento , Criança , Pré-Escolar , Traumatismos Craniocerebrais/complicações , Humanos , Hipertensão Intracraniana/complicações , Masculino , Trombose dos Seios Intracranianos/complicações , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fratura do Crânio com Afundamento/cirurgia , Seio Sagital Superior/diagnóstico por imagem , Seio Sagital Superior/cirurgia
12.
Chin J Traumatol ; 25(2): 115-117, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34419336

RESUMO

It is extremely dangerous to treat the posterior third of the superior sagittal sinus (PTSSS) surgically, since it is usually not completely ligated. In this report, the authors described the case of a 27-year-old man with a ruptured and defective PTSSS caused by an open depressed skull fracture, which was treated by ligation of the PTSSS and the patient achieved a positive recovery. The patient's occiput was hit by a height-limiting rod and was in a mild coma. A CT scan showed an open depressed skull fracture overlying the PTSSS and a diffuse brain swelling. He underwent emergency surgery. When the skull fragments were removed, a 4 cm segment of the superior sagittal sinus (SSS) and the adjacent dura mater were removed together with bone fragments. Haemorrhage occurred and blood pressure dropped. We completed the operation by ligating the severed ends of the fractured sagittal sinus. One month after the operation, apart from visual field defects, he recovered well. In our opinion, in primary hospitals, when patients with severely injured PTSSS cannot sustain a long-time and complicated operation, e.g., the bypass using venous graft, and face life-threatening conditions, ligation of the PTSSS is another option, which may unexpectedly achieve good results.


Assuntos
Fratura do Crânio com Afundamento , Seio Sagital Superior , Adulto , Cavidades Cranianas , Humanos , Masculino , Fratura do Crânio com Afundamento/complicações , Fratura do Crânio com Afundamento/cirurgia , Seio Sagital Superior/cirurgia , Tomografia Computadorizada por Raios X
13.
Artigo em Russo | MEDLINE | ID: mdl-35170282

RESUMO

Depressed skull fractures (ping-pong) in the fetus and newborn are associated with birth canal pathology, maternal trauma and birth trauma following instrumental delivery. The authors report a newborn with a depressed skull fracture (ping-pong) who underwent minimally invasive neurosurgical lifting of bone fragment through a burr hole. Strategy and methods of treatment of similar depressed skull fractures were comprehensively discussed. Moreover, the authors proposed a brief algorithm for the use of vacuum systems and various surgical techniques, including follow-up depending on type, cause, size of the fracture and concomitant intracranial lesions.


Assuntos
Fratura do Crânio com Afundamento , Fraturas Cranianas , Humanos , Recém-Nascido , Crânio , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fratura do Crânio com Afundamento/cirurgia , Fraturas Cranianas/diagnóstico por imagem , Fraturas Cranianas/cirurgia , Trepanação
14.
Childs Nerv Syst ; 37(6): 2045-2049, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33712872

RESUMO

OBJECTIVE: The aim of this paper is to describe a low-cost and readily accessed Manual Aspiration Reduction System (MARS) for use treating neonatal ping-pong fractures. METHODS: The MARS is composed of a pediatric anesthesia mask, part of a macro dripper, a 3-way stopcock, and two 60-ml syringes. Prior to its use in our patient, the system was tested on five adult volunteers to maximum negative pressure, and none reported pain during the procedure or experienced any other complication. CLINICAL CASE: A 15-day-old premature girl presented with a congenital ping-pong fracture. Her skull X-ray revealed a right parietal fracture. Neurological examination and transfontanellar ultrasound were normal. Treatment using the MARS was performed at the patient's bedside without sedation or anesthesia. The patient was monitored by the neonatology team throughout. RESULTS: Skull radiography revealed reduction of the fracture after the procedure performed with the MARS. The transfontanellar ultrasound and follow-up neurological examination were normal. The patient progressed favorably and was discharged from our service after 24 h. CONCLUSIONS: Due to its components, the MARS is a low-cost and readily accessed system. In this case, it permitted satisfactory reduction of a ping-pong parietal fracture. This system should greatly simplify the treatment of such fractures.


Assuntos
Anestesia , Fraturas Ósseas , Procedimentos de Cirurgia Plástica , Fratura do Crânio com Afundamento , Criança , Feminino , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Humanos , Recém-Nascido , Radiografia , Fratura do Crânio com Afundamento/cirurgia
15.
Anaerobe ; 65: 102264, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32860932

RESUMO

Desulfovibrio spp. are gram negative, obligate anaerobes capable of reducing sulfate. They have caused infections in humans, but very rarely. They are slow growers and difficult to identify. Hence, they are often overlooked and their actual presence goes unnoticed. Here, we describe a case of a 15- year old boy who was involved in a road traffic accident and he presented with seropurulent discharge from a depressed fracture wound on the forehead. Desulfovibrio vulgaris (D.vulgaris), was isolated from the pus discharge, the first to be reported. The characteristic desulfoviridin pigment production in the organism aided in the identification. The infection was successfully managed with pain reliever and course of amoxicillin - clavulanic acid and linezolid.


Assuntos
Desulfovibrio vulgaris/isolamento & purificação , Infecções por Desulfovibrionaceae/diagnóstico , Infecções por Desulfovibrionaceae/microbiologia , Testa/lesões , Fratura do Crânio com Afundamento/complicações , Infecção dos Ferimentos/diagnóstico , Infecção dos Ferimentos/microbiologia , Adolescente , Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Desulfovibrio vulgaris/classificação , Desulfovibrio vulgaris/efeitos dos fármacos , Infecções por Desulfovibrionaceae/tratamento farmacológico , Humanos , Masculino , Fenótipo , Infecção dos Ferimentos/tratamento farmacológico
16.
Br J Neurosurg ; 34(2): 219-223, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29363350

RESUMO

Elevation of a depressed skull fracture (DSF) overlying a venous sinus is generally avoided due to risk of sinus injury. Rarely, the sinus may be compressed by the fractured segment, causing intracranial hypertension (IH) or encephalopathy and can only be diagnosed with cerebral angiography or MR imaging techniques. The posterior third of the superior sagittal sinus (SSS) was found involved in all the reported cases. There is no consensus on its management, but most patients did not have any sinus thrombosis and improved after elevation of the compressing DSF alone. There are isolated reports of improvement with serial lumbar punctures or ventriculoperitoneal shunt.We report for the first time, a single session lumboperitoneal shunt and DSF elevation for a patient with thrombosis of the posterior part of SSS due to an overlying DSF, causing florid papilledema and impending blindness. Elevation of the DSF alone would not have achieved patency of the thrombosed sinus immediately to save his vision. Hence a lumboperitoneal shunt was done for immediate relief of IH. This CSF diversion alone was insufficient to achieve patency of the thrombosed sinus in the presence of significant external compression by the DSF; even if anticoagulants were used. Hence we elevated the DSF after craniotomy using a technical modification; by making a wide gutter circumferentially around the DSF with a high speed drill, to avoid sinus injury; prior to its elevation. The patient's vision improved in 48 hours and anticoagulants were used till 2 months when sinuses were found normal on MRI. Serial CT &MR images showing progression to thrombosis and recovery after decompression are presented. Both CSF diversion and DSF elevation are necessary when vision is threatened by IH due to sinus thrombosis with an overlying DSF.


Assuntos
Trombose dos Seios Intracranianos , Fratura do Crânio com Afundamento , Descompressão , Humanos , Hipertensão Intracraniana , Trombose dos Seios Intracranianos/etiologia , Fratura do Crânio com Afundamento/complicações , Seio Sagital Superior
17.
J Craniofac Surg ; 31(7): e732-e735, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32649557

RESUMO

Linear skull fractures are relatively common in children, however, it is rarer to see depressed fractures. This report details the case of a 7-year-old boy who was admitted to the emergency department with complete blindness after having experienced an in-car traffic accident. Brain tomography of the patient showed that a large, island-shaped piece of occipital bone was depressed on the visual cortex and superior sagittal sinus in the midline. Presentation of complete loss of vision after an isolated head trauma is very rare, and there are no similar cases in existing literature. The limits of surgical indications for depressed skull fractures are well established in neurosurgical practice. Surgical intervention should be performed immediately, especially in cases where neurological changes develop in the earliest stages after a trauma. The patient underwent emergency surgery to correct the blindness without affecting the vascular neighborhood. The depressed cranium was raised to its original position. The blindness had completely resolved shortly after the patient woke up during the postoperative period.


Assuntos
Cegueira Cortical/etiologia , Traumatismos Craniocerebrais/cirurgia , Osso Occipital/cirurgia , Fratura do Crânio com Afundamento/cirurgia , Seio Sagital Superior/cirurgia , Acidentes de Trânsito , Doença Aguda , Criança , Traumatismos Craniocerebrais/complicações , Traumatismos Craniocerebrais/diagnóstico por imagem , Humanos , Masculino , Osso Occipital/diagnóstico por imagem , Osso Occipital/lesões , Fratura do Crânio com Afundamento/diagnóstico por imagem , Seio Sagital Superior/diagnóstico por imagem
18.
Forensic Sci Med Pathol ; 16(4): 649-658, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32915387

RESUMO

Human skeletal remains of an adult male (20-24 years old) and a juvenile (4-8 years old), dated to 750 ± 85 14C years BP, were found on the southern margin of Mar Chiquita Lagoon (Córdoba, Argentina). Both individuals show signs of being victims of interpersonal violence, with arrowheads associated with the remains and perimortem lesions on the juvenile, as well as an unusual form of burial, with the juvenile partially overlapped with the adult. The aim of this work is to study a possible kin relationship between these two individuals through ancient DNA analysis. Biological kinship was evaluated by autosomal and Y-chromosome STR (short tandem repeat) typing, PCR-APLP for SNP determination and hypervariable region I sequencing of the mitochondrial DNA. Genetic analyses indicated that these individuals shared the same Y-chromosomal haplotype but different mitochondrial lineages. The likelihood ratio based on autosomal loci indicates that the genetic profiles of the human remains would be more likely to be that indicating a father-son bond. The paleogenetic approach combined with forensic genetic methods applied to this study allowed us to confirm a hypothesis that originated in bioarchaeological evidence. This study constitutes a unique case in Argentina of kinship determination based on DNA profiles of human remains in an archaeological context of interpersonal violence. It is important to highlight the contribution made by these studies to address topics usually hidden in bioarchaeological studies, such as community organization, cultural customs and mortuary practices.


Assuntos
Cromossomos Humanos Y , Impressões Digitais de DNA , Repetições de Microssatélites , Linhagem , Abuso Físico , Argentina , Sepultamento , Criança , Pré-Escolar , DNA Mitocondrial/genética , Eletroforese Capilar , Antropologia Forense , Genética Forense , Haplótipos , História Antiga , Humanos , Masculino , Reação em Cadeia da Polimerase , Polimorfismo de Nucleotídeo Único , Fraturas das Costelas , Fratura do Crânio com Afundamento , Adulto Jovem
19.
Ann Emerg Med ; 74(1): 1-10, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-30655017

RESUMO

STUDY OBJECTIVE: Existing clinical decision rules guide management for head-injured children presenting 24 hours or sooner after injury, even though some may present greater than 24 hours afterward. We seek to determine the prevalence of traumatic brain injuries for patients presenting to emergency departments greater than 24 hours after injury and identify symptoms and signs to guide management. METHODS: This was a planned secondary analysis of the Australasian Paediatric Head Injury Rule Study, concentrating on first presentations greater than 24 hours after injury, with Glasgow Coma Scale scores 14 and 15. We sought associations with predictors of traumatic brain injury on computed tomography (CT) and clinically important traumatic brain injury. RESULTS: Of 19,765 eligible children, 981 (5.0%) presented greater than 24 hours after injury, and 465 injuries (48.5%) resulted from falls less than 1 m and 37 (3.8%) involved traffic incidents. Features associated significantly with presenting greater than 24 hours after injury in comparison with presenting within 24 hours were nonfrontal scalp hematoma (20.8% versus 18.1%), headache (31.6% versus 19.9%), vomiting (30.0% versus 16.3%), and assault with nonaccidental injury concerns (1.4% versus 0.4%). Traumatic brain injury on CT occurred in 37 patients (3.8%), including suspicion of depressed skull fracture (8 [0.8%]) and intracranial hemorrhage (31 [3.8%]). Clinically important traumatic brain injury occurred in 8 patients (0.8%), with 2 (0.2%) requiring neurosurgery, with no deaths. Suspicion of depressed skull fracture was associated with traumatic brain injury on CT consistently, with the only other significant factor being nonfrontal scalp hematoma (odds ratio 19.0; 95% confidence interval 8.2 to 43.9). Clinically important traumatic brain injury was also associated with nonfrontal scalp hematoma (odds ratio 11.7; 95% confidence interval 2.4 to 58.6) and suspicion of depressed fracture (odds ratio 19.7; 95% confidence interval 2.1 to 182.1). CONCLUSION: Delayed presentation after head injury, although infrequent, is significantly associated with traumatic brain injury. Evaluation of delayed presentations must consider identified factors associated with this increased risk.


Assuntos
Lesões Encefálicas Traumáticas/complicações , Lesões Encefálicas Traumáticas/epidemiologia , Tempo para o Tratamento/estatística & dados numéricos , Adolescente , Australásia/epidemiologia , Lesões Encefálicas Traumáticas/diagnóstico por imagem , Criança , Pré-Escolar , Tomada de Decisão Clínica , Serviço Hospitalar de Emergência , Feminino , Escala de Coma de Glasgow , Cefaleia/diagnóstico , Cefaleia/epidemiologia , Hematoma/epidemiologia , Hematoma/patologia , Humanos , Lactente , Hemorragias Intracranianas/diagnóstico , Hemorragias Intracranianas/epidemiologia , Masculino , Prevalência , Couro Cabeludo/patologia , Fratura do Crânio com Afundamento/diagnóstico por imagem , Fratura do Crânio com Afundamento/epidemiologia , Fratura do Crânio com Afundamento/etiologia , Tomografia Computadorizada por Raios X/métodos , Vômito/diagnóstico , Vômito/epidemiologia
20.
Childs Nerv Syst ; 35(11): 2233-2236, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31037423

RESUMO

BACKGROUND: Sutural or Wormian bones are accessory bones of genetic and hereditary relevance, considered as ethnic and anatomical variables. Recently, they have been related to a certain type of congenital alterations such as osteogenesis imperfecta; however, there is no description in the literature of their involvement in skull fractures in infants. CASE PRESENTATION: We present a case of a male patient aged 15 months who suffered a fall from the stairs of his home approximately 6 h before arrival in the emergency room. This fall of approximately 1 m in height and with an area of direct impact on the right occipito-parietal region with no apparent loss of consciousness. At admission, with a Glasgow of 14 for irritability with subgaleal hematoma and cranial endostosis on occipitoparietal region, no more neurological signs were present. A CT scan of the skull was performed showing an occipital-parietal discontinuity at the lambdoid suture, and the scan also showed that a displacement occurred below the thickness of the adjacent bone. In addition, radiographic evidence showed a high possibility of dural penetration and an area of adjacent hemorrhagic contusion. Due to these findings, a surgical approach was decided upon. The findings in the surgical procedure were a complete dislocation (rupture) of lambdoidal cranial suture on the occipital border of the accessory bone (Wormian bone) with dura mater tear on the rupture tracing. A craniotomy was performed with dural plasty without eventualities. Forty-eight hours after surgery, he was discharged home in a stable neurologic condition. CONCLUSIONS: The present report shows the implications of approaching this type of injury, which can be confused as a depressed skull fracture. There is no description in the literature of a sutural rupture associated with Wormian bones.


Assuntos
Suturas Cranianas/lesões , Dura-Máter/lesões , Luxações Articulares/diagnóstico por imagem , Osso Occipital/diagnóstico por imagem , Osso Parietal/diagnóstico por imagem , Ruptura/diagnóstico por imagem , Fratura do Crânio com Afundamento/diagnóstico , Acidentes por Quedas , Anticorpos Monoclonais , Contusão Encefálica , Suturas Cranianas/diagnóstico por imagem , Craniotomia , Diagnóstico Diferencial , Dura-Máter/cirurgia , Humanos , Imageamento Tridimensional , Lactente , Luxações Articulares/complicações , Luxações Articulares/cirurgia , Masculino , Procedimentos de Cirurgia Plástica , Ruptura/cirurgia , Tomografia Computadorizada por Raios X
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