1.
Biosci Biotechnol Biochem
; 73(9): 2110-2, 2009 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19734657
RESUMO
This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells. It had no cytotoxicity on RBL-2H3 cells. These results show that GSE is a candidate for effective therapeutic material for allergic diseases.