Impairment of myocardial functions and arterial stiffness in patients with lichen planus
An. bras. dermatol
; An. bras. dermatol;95(2): 180-186, Mar.-Apr. 2020. tab, graf
Article
em En
| LILACS, ColecionaSUS
| ID: biblio-1130838
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Background:
Lichen planus is a chronic inflammatory mucocutaneous disease. Recent studies have suggested that it is associated with an increased risk of cardiovascular comorbidities.Objective:
The purpose of this study was to assess and compare arterial stiffness and cardiovascular hemodynamics in patients with lichen planus and a healthy control group.Methods:
Fifty-five patients with lichen planus and 42 healthy controls were enrolled. All patients underwent echocardiographic examination, and arterial stiffness was measured using applanation tonometry.Results:
No statistically significant difference was determined between the patient and control groups in terms of arterial stiffness, but stiffness was markedly higher in patients with erosive lichen planus compared to the control group and other patients (p = 0.006, and p = 0.023, respectively). Moderate positive correlation was determined between duration of disease and arterial stiffness. Impairment of systolic and diastolic functions was also determined in patients with lichen planus compared to the control group (p < 0.001, and p = 0.005, respectively). Studylimitations:
Relatively low number of patients.Conclusion:
The positive correlation observed between duration of disease and arterial stiffness in patients with lichen planus suggests that these patients should be followed-up in terms of cardiovascular risk in the presence of resistant and long-term disease, particularly in case of erosive lichen planus.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
/
ColecionaSUS
Assunto principal:
Doenças Cardiovasculares
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Rigidez Vascular
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Hemodinâmica
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Líquen Plano
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
/
Male
Idioma:
En
Revista:
ABD: Anais brasileiros de dermatologia
/
An Bras Dermatol
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An. bras. dermatol
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An. bras. dermatol. (Online)
/
Anais brasileiros de dermatologia (Impresso)
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Turquia