Outbreak of acute gastro enteritis in young children with death due to rotavirus genotype G9 in Rio Branco,Brazilian Amazon region, 2005
Int. j. infect. dis
; 14(10): 898-903, 2010. tab, ilus, graf, mapas
Article
em En
| BVSDIP, FIOCRUZ
| ID: dip-3028
Biblioteca responsável:
BR275.1
Localização: BR275.1; PCIEC2010
ABSTRACT
An epidemic of acute gastroenteritis occurred in Rio Branco City, Acre State, in Brazil's Amazon region in 2005. An investigation was conducted to confirm the etiology and identify possible risk factors for death. Methods:
Rio Branco municipality surveillance data for the period May to October 2005 were reviewed. In a casecontrol study, children who died following acute gastroenteritis were compared to age-matched controls with acute gastroenteritis who survived. Rotavirus A (RV-A) was investigated in 799 stool samples and genotyped by reverse transcription polymerase chain reaction (RT-PCR).Results:
The cumulative incidence of diarrhea in children aged <5 years was 21 percent. A fatal outcome was significantly associated with uncovered household water storage containers. RV-A was identified in 88 percent of samples and G9 was the prevalent genotype (71 percent).Conclusions:
Oral rehydration solution and boiling or chlorinating drinking water likely limited mortality. This epidemic was caused by RV-A genotype G9. After the outbreak, a rotavirus vaccine was introduced into the official childhood immunization schedule in Brazil.(AU)
Texto completo:
1
Base de dados:
BVSDIP
/
FIOCRUZ
Assunto principal:
Surtos de Doenças
/
Rotavirus
/
Gastroenterite
Limite:
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Int. j. infect. dis
Ano de publicação:
2010
Tipo de documento:
Article