Propolis: anti-Staphylococcus aureus activity and synergism with antimicrobial drugs
Mem. Inst. Oswaldo Cruz
; 100(5): 563-566, Aug. 2005. graf
Article
em En
| LILACS
| ID: lil-409976
Biblioteca responsável:
BR1.1
ABSTRACT
Propolis is a natural resinous substance collected by bees from tree exudates and secretions. Its antimicrobial activity has been investigated and inhibitory action on Staphylococcus aureus growth was evaluated. The in vitro synergism between ethanolic extract of propolis (EEP) and antimicrobial drugs by two susceptibility tests (Kirby and Bauer and E-Test) on 25 S. aureus strains was evaluated. Petri dishes with sub-inhibitory concentrations of EEP were incubated with 13 drugs using Kirby and Bauer method and synergism between EEP and five drugs [choramphenicol (CLO), gentamicin (GEN), netilmicin (NET), tetracycline (TET), and vancomycin (VAN)] was observed. Nine drugs were assayed by the E-test method and five of them exhibited a synergism [CLO, GEN, NET, TET, and clindamycin (CLI)]. The results demonstrated the synergism between EEP and antimicrobial drugs, especially those agents that interfere on bacterial protein synthesis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Própole
/
Staphylococcus aureus
/
Antibacterianos
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
MEDICINA TROPICAL
/
PARASITOLOGIA
Ano de publicação:
2005
Tipo de documento:
Article