G-CSF (Granulocyte Colony-Stimulating Factor): follow-up and use in a French University hospital.
Can J Hosp Pharm
; 48(2): 90-7, 1995 Apr.
Article
em En
| MEDLINE
| ID: mdl-10142843
ABSTRACT
Granulocyte Colony-Stimulating Factor or G-CSF (NEUPOGEN) was approved for use in France in November 1991 for prevention of chemotherapy-induced neutropenia. This retrospective study was conducted at Saint-Louis Hospital, Paris, France, from November 1991 to March 1993 with a more detailed analysis of patient profiles for courses ordered between November 1991 and December 1992. Data were collected on standardized G-CSF-treatment summary forms. The purpose of the study was to define, in clinical terms, the patients treated by G-CSF to determine the average cost per course of therapy and its impact on the hospital pharmacy budget. From November 1991 to December 1992 data from 307 patient profiles were collected and analyzed. The subcutaneous route was the preferred route and only 16.6% of courses were administered intravenously. 45.6% of patients received a single course, 24.3% received two courses, and 30.1% received more than two courses. Each patient completed an average of 2.3 courses at an average cost per course of $2,000.00 (Canadian dollars). During March 1993, 50% of vials dispensed were administered to outpatients. During the 14-month period, an average of 613.8 vials were dispensed per month corresponding to an average monthly expenditure of $104,000.00 (Canadian dollars). In the first 12 months following the commercial availability of G-CSF, G-CSF expenditures accounted for 8% of the pharmacy budget.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Serviço de Farmácia Hospitalar
/
Serviço Hospitalar de Oncologia
/
Custos de Medicamentos
/
Receptores de Fator Estimulador de Colônias de Granulócitos
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Humans
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Can J Hosp Pharm
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
França