Effect of electroacupuncture on the activities of tyrosine protein kinase in subcellular fractions of activated T lymphocytes from the traumatized rats.
Acupunct Electrother Res
; 23(3-4): 161-70, 1998.
Article
em En
| MEDLINE
| ID: mdl-10193701
ABSTRACT
The present study was to observe the dynamic changes of tyrosine protein kinase (TPK) activity in subcellular fractions in the early stage of activation of T lymphocytes from normal and traumatized rats, and the regulatory effect of electroacupuncture (EA) stimulation on it. The results showed that the activities of TPK in membranous and cytosolic fractions of activated T lymphocytes were increased on second 5, and the peak was on scond 45 after ConA stimulation. Then it was decreased gradually. Comparing with the control group, the activities of TPK in membranous and cytosolic fractions of activated T lymphocytes from the traumatized rats were inhibited in various degrees especially in membrane. EA of "Zusanli"(ST-36) and "Lanwei"(Extra 33) points could enhance the activity of TPK in subcellular fractions of activated T lymphocytes from the traumatized rats. The results indicated that EA stimulation could prevent the inhibition of activation of TPK induced by trauma stress, and contribute to transmembrane signal transduction of T lymphocytes.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Fisiológico
/
Ferimentos e Lesões
/
Proteínas Tirosina Quinases
/
Linfócitos T
/
Transdução de Sinais
/
Eletroacupuntura
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Acupunct Electrother Res
Ano de publicação:
1998
Tipo de documento:
Article