n-3 fatty acids in the prevention of cardiac arrhythmias.
Lipids
; 34 Suppl: S187-9, 1999.
Article
em En
| MEDLINE
| ID: mdl-10419144
ABSTRACT
In animals and probably in humans n-3 polyunsaturated fatty acids (PUFA) are antiarrhythmic. A report follows on the recent studies of the antiarrhythmic actions of PUFA. The PUFA stabilize the electrical activity of isolated cardiac myocytes by inhibiting sarcolemmal ion channels, so that a stronger electrical stimulus is required to elicit an action potential and the relative refractory period is markedly prolonged. This appears at present to be the probable major antiarrhythmic mechanism of PUFA.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arritmias Cardíacas
/
Ácidos Graxos Ômega-3
/
Coração
/
Antiarrítmicos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Lipids
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos