The anatomy and cell biology of peripheral myelin protein-22.
Ann N Y Acad Sci
; 883: 143-51, 1999 Sep 14.
Article
em En
| MEDLINE
| ID: mdl-10586240
ABSTRACT
The gain of function phenotypes exhibited by the heterozygous Tr, Tr-J, and CMT1A mutations indicate that these mutations interfere with more than the function of a single PMP22 allele. The identification of proteins that interact with PMP22 and that are sensitive both to stoichiometry and the effects of the mutations could provide important leads to a unified hypothesis to explain the riddle of the PMP22-related neuropathies.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Charcot-Marie-Tooth
/
Proteínas da Mielina
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Ann N Y Acad Sci
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Canadá