Hemodynamic role of the circle of Willis in stenoses of internal carotid arteries. An analytical solution of a linear model.
J Biomech
; 33(4): 395-405, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10768388
ABSTRACT
A mathematical model of blood flow through the circle of Willis was developed, within a linear framework. Comprehensive analytical solutions, including a remarkably small number of parameters, were derived in the cases of obstructive lesions of extracranial carotid arteries. The influence of these lesions and the role of anterior and posterior communicating arteries on the blood pressure at the entry of the cerebral territories were quantified and analyzed emphasizing that the responses of the system of Willis to obstructive carotid lesions are extremely varied, depending on the communicating artery anatomy. Comparison with numerical results obtained by using a non-linear model showed no physiologically significant differences. Such a model might be an essential tool for an accurate assessment of the cerebral hemodynamics in carotid diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Circulação Cerebrovascular
/
Círculo Arterial do Cérebro
/
Estenose das Carótidas
/
Modelos Cardiovasculares
Limite:
Humans
Idioma:
En
Revista:
J Biomech
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
França