Defibrotide in recurrent thrombotic thrombocytopenic purpura.
Clin Appl Thromb Hemost
; 6(2): 69-70, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10775024
ABSTRACT
Thrombotic thrombocytopenic purpura (TTP) is a common illness characterized by platelet thrombi within the microvascularization. In its natural course, this disease has had a mortality rate of 90%. Plasma infusion or exchange achieved a survival rate of 70% to 90%. However, 10% to 30% of patients surviving the initial TTP episode relapse at regular intervals. The treatment of recurrent forms of the disease remains a challenge; several approaches have been shown to induce medium to long term remissions. We describe a patient with recurrent TTP whose disease remitted after administration of defibrotide.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polidesoxirribonucleotídeos
/
Púrpura Trombocitopênica Trombótica
/
Inibidores da Agregação Plaquetária
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Clin Appl Thromb Hemost
Assunto da revista:
ANGIOLOGIA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Itália