Serum tryptase and the laboratory diagnosis of systemic mastocytosis.
Hematol Oncol Clin North Am
; 14(3): 641-57, 2000 Jun.
Article
em En
| MEDLINE
| ID: mdl-10909044
ABSTRACT
Total tryptase levels of 20 ng/mL or higher in a baseline serum sample when the ratio of total to beta-tryptase is 20 or greater strongly suggest underlying systemic mastocytosis. Whether these criteria prove to be more sensitive than a bone marrow biopsy will require further study. Although the absolute level of total tryptase does not predict disease severity, it may provide a practical method for assessing the efficacy of therapeutic interventions designed to reduce the mast cell burden.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Mastocitose
/
Serina Endopeptidases
/
Isoenzimas
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Hematol Oncol Clin North Am
Assunto da revista:
HEMATOLOGIA
/
NEOPLASIAS
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos