The effect of antibacterial soap with 1.5% triclocarban on Staphylococcus aureus in patients with atopic dermatitis.
Cutis
; 66(4): 296-300, 2000 Oct.
Article
em En
| MEDLINE
| ID: mdl-11109156
ABSTRACT
This double-blind study determined whether daily bathing with an antibacterial soap would reduce the number of Staphylococcus aureus on the skin and result in clinical improvement of atopic dermatitis. For 9 weeks, 50 patients with moderately severe atopic dermatitis bathed daily with either an antimicrobial soap containing 1.5% triclocarban or the placebo soap. They also used a nonmedicated moisturizer and 0.025% triamcinolone acetonide cream as needed, but the availability of the corticosteroid cream was discontinued after 6 weeks. The antimicrobial soap regimen caused significantly greater improvement in the severity and extent of skin lesions than the placebo soap regimen, which correlated with reductions both in S aureus in patients with positive cultures at baseline and in total aerobic organisms. Outcome measures included reductions in S aureus, total aerobic organisms, and dermatologic assessments. Overall, daily bathing with an antibacterial soap was well tolerated, provided clinical improvement, and reduced levels of skin microorganisms.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Staphylococcus aureus
/
Banhos
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Infecções Cutâneas Estafilocócicas
/
Carbanilidas
/
Dermatite Atópica
/
Anti-Infecciosos Locais
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
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Adult
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Aged
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Child
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Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cutis
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos