Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis We thank Dr. C. Khosla and Dr. Y. Hayakawa for generous gifts of apoptolidin, and Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for Chemical Biology, American Biosciences, a predoctoral fellowship from Boehringer Ingelheim (to Y.L.), a postdoctoral fellowship the George Hewitt Foundation (to K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough.

Nicolaou, K. C.; Li, Yiwei; Fylaktakidou, Konstantina C.; Mitchell, Helen J.; Sugita, Kazuyuki

Nicolaou, K. C.; Li, Yiwei; Fylaktakidou, Konstantina C.; Mitchell, Helen J.; Sugita, Kazuyuki.

Afiliação

Nicolaou KC; Department of Chemistry and The Skaggs Institute for Chemical Biology The Scripps Research Institute 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA).

Angew Chem Int Ed Engl ; 40(20): 3854-3857, 2001 Oct 15.

Article em En | MEDLINE | ID: mdl-11668554

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Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Health_economic_evaluation Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2001 Tipo de documento: Article

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