Prospects for chemoprevention of cancer.
J Intern Med
; 251(4): 286-300, 2002 Apr.
Article
em En
| MEDLINE
| ID: mdl-11952879
ABSTRACT
The recent progress in molecular biology and pharmacology has increased the likelihood that cancer prevention will rely increasingly on interventions collectively termed 'chemoprevention'. Cancer chemoprevention is the use of agents to inhibit, delay or reverse carcinogenesis. A number of potential targets for chemoprevention have recently been identified. Many classes of agents including antioestrogens, anti-inflammatories, antioxidants and other diet-derived agents have shown a great deal of promise. In this review, we will begin by describing the general classes of chemopreventive agents and the mechanisms by which these agents act. We will then describe the opportunities that presently exist for chemoprevention of specific cancers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Quimioprevenção
/
Moduladores de Receptor Estrogênico
/
Antagonistas de Androgênios
/
Neoplasias
/
Antioxidantes
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Intern Med
Assunto da revista:
MEDICINA INTERNA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos