Opening the high-pressure domain beyond 2 kbar to protein and virus crystallography--technical advance.
Structure
; 10(10): 1409-14, 2002 Oct.
Article
em En
| MEDLINE
| ID: mdl-12377126
ABSTRACT
The combined use of a diamond anvil cell and ultrashort-wavelength undulator radiation has allowed the collection of high-resolution diffraction data from protein and virus crystals submitted to hydrostatic pressures beyond 2 kbar. Crystals of cubic cowpea mosaic virus (CPMV) can be compressed to at least 3.5 kbar. Diffraction from CPMV crystals displaying an unusual disorder at atmospheric pressure was considerably enhanced by application of pressure. These experiments suggest that pressure may be used in some cases to improve order in crystals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vírus
/
Proteínas
/
Cristalografia
Idioma:
En
Revista:
Structure
Assunto da revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
/
BIOTECNOLOGIA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
França