Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine.
Chem Commun (Camb)
; (23): 2860-1, 2002 Dec 07.
Article
em En
| MEDLINE
| ID: mdl-12478783
ABSTRACT
The gene btrR from Bacillus circulans has been cloned and expressed and shown to produce a protein which catalyses the transamination of 2-deoxy-scyllo-inosose to give 2-deoxy-scyllo-inosamine, an intermediate in the biosynthesis of 2-deoxystreptamine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transaminases
/
Hexosaminas
/
Antibacterianos
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2002
Tipo de documento:
Article