Synthesis and antibacterial activity of 1,3-diarylpyrimido[4,5-d]pyrimidines.

ABSTRACT

This paper describes the synthesis of 4,5-diaminoderivatives of pyrimidine and pyrimido [4,5-d] pyrimidines and evaluation of their antibacterial activity on 9 selected bacterial species relatif the changes in the chemical structure to an increase in the bioactive properties.