On the relation between ERG waves and retinal function: inverted rod photoresponses from the frog retina.
Vision Res
; 32(8): 1411-6, 1992 Aug.
Article
em En
| MEDLINE
| ID: mdl-1455714
ABSTRACT
In rod mass receptor photoresponses recorded across the isolated frog retina, a paradoxical cornea-positive wave may precede the response of normal polarity. We present a model which shows that the light-induced decrease in rod current can give rise to inverted or biphasic ERG signals if the distal part (tip) of the rod outer segment responds more slowly and/or less sensitively than the proximal part (base). The condition is that current entering at the tip is represented with greater weight in the ERG. The model reproduces recorded ERG waveforms well. It further predicts that if there is a light-insensitive conductance in the tip membrane, ERG photoresponses may be non-recordable although current photoresponses are only slightly reduced. The model reveals a type of complexity in the relation between mass potentials and underlying physiological processes which has not previously received attention.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células Fotorreceptoras
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Vision Res
Ano de publicação:
1992
Tipo de documento:
Article