The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Nat Genet
; 36(11): 1133-7, 2004 Nov.
Article
em En
| MEDLINE
| ID: mdl-15514660
ABSTRACT
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cruzamento
/
Recursos em Saúde
/
Camundongos Endogâmicos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Genet
Assunto da revista:
GENETICA MEDICA
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Estados Unidos