Human embryonic stem cell lines derived from the Chinese population.
Cell Res
; 15(5): 394-400, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15916726
ABSTRACT
Six human embryonic stem cell lines were established from surplus blastocysts. The cell lines expressed alkaline phosphatase and molecules typical of primate embryonic stem cells, including Oct-4, Nanog, TDGF1, Sox2, EBAF, Thy-1, FGF4, Rex-1, SSEA-3, SSEA-4, TRA-1-60 and TRA-1-81. Five of the six lines formed embryoid bodies that expressed markers of a variety of cell types; four of them formed teratomas with tissue types representative of all three embryonic germ layers. These human embryonic stem cells are capable of producing clones of undifferentiated morphology, and one of them was propagated to become a subline. Human embryonic stem cell lines from the Chinese population should facilitate stem cell research and may be valuable in studies of population genetics and ecology.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linhagem Celular
/
Células-Tronco Embrionárias
Limite:
Animals
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Cell Res
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
China